… -glycans significantly reduces the spread of SARS-CoV-2 infection in vitro, including that of several variants. As new SARS-CoV-… N-glycans, we hypothesized that the partial or complete …
X Ai, D Wang, A Honko, Y Duan, I Gavrish… - Journal of the …, 2021 - ACS Publications
… higher inhibition of viral infectivity. Overall, our results show that surface glycan modification is … boost cellular nanosponges against glycan-dependent viral threats such as SARS-CoV-2. …
… Especially, inhibition of the N-glycan biosynthesis pathway … The chemical inhibitors of SARS-CoV-2 glycosylation could … inhibitors (both natural and synthetically designed inhibitors) of …
… in cells by inhibiting the first step in the biosynthesis of N-linked glycans in proteins resulting in many misfolded proteins [7]. When the antibiotic blocks glycosylation of N-glycans, the …
AJ Guseman, LJ Rennick, S Nambulli… - Proceedings of the …, 2023 - National Acad Sciences
… inhibits all tested variants of concern as well as SARS-CoV 2003, establishing that multivalent glycan-targeting molecules have the potential to act as pan-coronavirusinhibitors. …
A Barre, EJM Van Damme, M Simplicien, S Le Poder… - Cells, 2021 - mdpi.com
… glycan probes for targeting the SARS-CoV, MERS-CoV, and … of complex glycans at the top of the SARS-CoV and SARS-CoV-… the Fabaceae, compared to MERS-CoV spikes (Figure 29). …
R Dwivedi, P Samanta, P Sharma, F Zhang… - Journal of Biological …, 2021 - ASBMB
… surface plasmon resonance of the wildtype SARS-CoV-2 spike (S)… Competitive surface plasmon resonance inhibition analysis of … molecule for future investigations against SARS-CoV-2. …
M Klevanski, H Kim, M Heilemann, T Kuner… - Antiviral Research, 2024 - Elsevier
… Allium porrum (leek) extract inhibitingSARS-CoV-2 infection in both … SARS-CoV-2 variants. We used multiplex super-resolution microscopy to address lectin interactions with SARS-CoV…
Y Cai, W Xu, C Gu, X Cai, D Qu, L Lu, Y Xie, S Jiang - Virologica Sinica, 2020 - Springer
… is highly effective in inhibiting the pseudotyped and live SARS-CoV-2 infection by … SARS-CoV-2 S protein, which is in consistent with the mechanism by which GRFT inhibitsSARS-CoV …