SARS-CoV-2 infection: host response, immunity, and therapeutic targets

P Shivshankar, H Karmouty-Quintana, T Mills… - Inflammation, 2022 - Springer
… cells counter barrier disruption, modulate host innate immune response to induce chemotaxis,
and … models to study SARS-CoV-2 infection, molecular pathways involved in SARS-CoV-2-…

Host immune response and immunobiology of human SARS-CoV-2 infection

S Kumar, R Nyodu, VK Maurya, SK Saxena - Coronavirus Disease 2019 …, 2020 - Springer
host–pathogen relationship and the host immune response during COVID-19 infection.
One of the recent developments regarding the understanding of SARS-CoV… into the SARS-CoV-2 …

[HTML][HTML] Imbalanced host response to SARS-CoV-2 drives development of COVID-19

D Blanco-Melo, BE Nilsson-Payant, WC Liu, S Uhl… - Cell, 2020 - cell.com
… and host response following SARS-CoV-2 infection. Here we offer an in-depth analysis of the
transcriptional response to SARS-CoV… Cell and animal models of SARS-CoV-2 infection, in …

Influenza virus and SARS-CoV-2: pathogenesis and host responses in the respiratory tract

T Flerlage, DF Boyd, V Meliopoulos… - Nature Reviews …, 2021 - nature.com
… , the contribution of the host response to severe clinical … SARS-CoV-2 and its disease
manifestations in humans, throughout the Review we discuss what is known about SARS-CoV-2 in …

Temporal and spatial heterogeneity of host response to SARS-CoV-2 pulmonary infection

N Desai, A Neyaz, A Szabolcs, AR Shih… - Nature …, 2020 - nature.com
The relationship of SARS-CoV-2 pulmonary infection and severity of disease is not fully
understood. Here we show analysis of autopsy specimens from 24 patients who succumbed to …

Large-scale plasma analysis revealed new mechanisms and molecules associated with the host response to SARS-CoV-2

E Barberis, S Timo, E Amede, VV Vanella… - International journal of …, 2020 - mdpi.com
… Our findings show a slightly different host response respect to the study mentioned above,
which … In particular, we found that the host response to the virus directly or indirectly involves …

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): An overview of viral structure and host response

I Astuti - Diabetes & Metabolic Syndrome: Clinical Research & …, 2020 - Elsevier
… RNA genome including SARS-CoV which has a 5 ′cap less than the host cell RNA makes
… immune response. To get around this, the virus developed a strategy of mimicking the host

Intestinal host response to SARS-CoV-2 infection and COVID-19 outcomes in patients with gastrointestinal symptoms

AE Livanos, D Jha, F Cossarini, AS Gonzalez-Reiche… - Gastroenterology, 2021 - Elsevier
response against SARS-CoV-2 from post mortem lung tissue 7 and human intestinal organoids.
Although we did not observe a substantial acute SARS-CoV-2 responseresponse genes …

[HTML][HTML] Transcriptomic similarities and differences in host response between SARS-CoV-2 and other viral infections

SA Thair, YD He, Y Hasin-Brumshtein, S Sakaram… - Iscience, 2021 - cell.com
… We here report on the results of a comparison of host responses to SARS-CoV-2 and other
viruses. We mapped out their similarities and differences at the gene level, pathway level, …

Exacerbated innate host response to SARS-CoV in aged non-human primates

SL Smits, A De Lang, JMA Van Den Brand… - PLoS …, 2010 - journals.plos.org
SARS-CoV-infected macaques regarding pathology, virus replication and host response,
insight into the pathogenesis of SARS-CoV is … the innate host response to SARS-CoV infection …