… To elucidate SARS-CoV-2-MP interactions we investigated transcriptomic and proteomic profiles of human monocyte-derived macrophages. While expression of the SARS-CoV-2 …
Z Zhang, R Penn, WS Barclay, ES Giotis - Viruses, 2022 - mdpi.com
… the ability of humanmacrophages to support SARS-CoV-2 replication. We infected monolayers of primary human monocyte-derived macrophages (MDM) with a SARS-CoV-2 B.1 …
… -stranded RNA (GU-rich RNA) derived from SARS-CoV-2, SARS-CoV-1, and HIV-1 trigger a … humanmacrophages in the absence of pyroptosis, with GU-rich RNA from the SARS-CoV-2 …
Q Lian, K Zhang, Z Zhang, F Duan, L Guo… - Nature …, 2022 - nature.com
… lung and macrophage co-culture system derived from human … SARS-CoV-2 infection. We find that both classically polarized macrophages (M1) and alternatively polarized macrophages …
… of SARS-CoV-2 spike protein S1 subunit (hereafter S1) on the pro-inflammatory responses in murine and humanmacrophages. Murine peritoneal exudate macrophages produced pro-…
Z Abassi, Y Knaney, T Karram, SN Heyman - Frontiers in Immunology, 2020 - frontiersin.org
… Herein we outline potential adverse effects of SARS-CoV2 on macrophages and … , while macrophages play an important role in antiviral defense mechanisms, in the case of SARS-CoV, …
A Kosyreva, D Dzhalilova, A Lokhonina… - Frontiers in …, 2021 - frontiersin.org
… macrophage phenotypes and functionalities. We describe participation of monocytes, monocyte-derived and resident lung macrophages in SARS-CoV-2… of reprogrammed …
W Fu, C Lei, Z Ma, K Qian, T Li, J Zhao… - Frontiers in …, 2021 - frontiersin.org
… As macrophages have unique effector functions as a first-line … humanmacrophages with chimeric antigen receptors (CARs) to reprogram their phagocytic activity against SARS-CoV-2. …
T Wallach, M Raden, L Hinkelmann, M Brehm… - Frontiers in …, 2023 - frontiersin.org
… secretion from the murine macrophage line RAW264.7 through TLR7/8 (64). Our data show that humanmacrophages significantly release TNF in response to the SARS-CoV-2 RNA …