[HTML][HTML] Inflammasomes and SARS-CoV-2 infection

J Kaivola, TA Nyman, S Matikainen - Viruses, 2021 - mdpi.com
… the molecular activation mechanisms of inflammasomes during SARS-CoV-2 virus infection
and … pathways in NLRP3 inflammasome activation and ARDS during SARS-CoV-2 infection. …

Inflammasomes are activated in response to SARS-CoV-2 infection and are associated with COVID-19 severity in patients

TS Rodrigues, KSG de Sá, AY Ishimoto… - Journal of Experimental …, 2021 - rupress.org
… speculated, the inflammasome activation and participation in … NLRP3 inflammasome is
activated in response to SARS-CoV-2 … with SARS-CoV-2 and assessed inflammasome activation. …

[HTML][HTML] SARS-CoV-2 N protein promotes NLRP3 inflammasome activation to induce hyperinflammation

P Pan, M Shen, Z Yu, W Ge, K Chen, M Tian… - Nature …, 2021 - nature.com
inflammasome activation. We also show that SARS-CoV-2 N protein promotes the assembly
of the NLRP3 inflammasome through direct interaction with NLRP3 protein. Moreover, …

[HTML][HTML] NLRP3 inflammasome activation and SARS-CoV-2-mediated hyperinflammation, cytokine storm and neurological syndromes

D Dutta, J Liu, H Xiong - International journal of physiology …, 2022 - ncbi.nlm.nih.gov
… progress on SARS-CoV-2-induced NLRP3 inflammasome activation, … inflammasome
activation induced by proteins of SARS-CoV-2. SARS-CoV-2 proteins-mediated NLRP3 activation

[HTML][HTML] Inflammasome activation at the crux of severe COVID-19

SM Vora, J Lieberman, H Wu - Nature Reviews Immunology, 2021 - nature.com
… Here we review evidence that SARS-CoV-2 directly or indirectly activates inflammasomes, …
We further discuss potential mechanisms of inflammasome activation and clinical efforts …

Inflammasome activation by SARS-CoV-2 and its participation in COVID-19 exacerbation

TS Rodrigues, DS Zamboni - Current Opinion in Immunology, 2023 - Elsevier
… that the virus engages the CASP4/11 (Caspase 4/11)-mediated noncanonical activation of
… the recent data regarding the activation of NLRP3 inflammasome by SARS-CoV-2 and their …

The NLRP3 inflammasome and COVID-19: Activation, pathogenesis and therapeutic strategies

N Zhao, B Di, L Xu - Cytokine & growth factor reviews, 2021 - Elsevier
… Therefore, the NLRP3 inflammasome can … inflammasome activation pathway. Second,
we review the cellular/molecular mechanisms of NLRP3 inflammasome activation by SARS-CoV-…

[HTML][HTML] Modulation of the NLRP3 inflammasome by Sars-CoV-2 Envelope protein

M Yalcinkaya, W Liu, MN Islam, AG Kotini… - Scientific reports, 2021 - nature.com
… effects of Sars-Cov-2 E protein on inflammasome activation. On … Sars-Cov-2 E protein
suppresses the ER stress response, inflammasome priming and NLRP3 inflammasome activation. …

[HTML][HTML] Innate immune response and inflammasome activation during SARS-CoV-2 infection

M Islamuddin, SA Mustfa, SNMN Ullah, U Omer, K Kato… - Inflammation, 2022 - Springer
… the innate immune response to SARS-CoV-2 infection and the virus’ evasion of the innate …
activation of the Nod-like receptor family, pyrin-domain-containing 3 (NLRP3) inflammasome

[HTML][HTML] SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein

EA Albornoz, AA Amarilla, N Modhiran, S Parker… - Molecular …, 2023 - nature.com
… To investigate microglial inflammasome activation in response to SARS-CoV-2, we exposed
MDMi cells to SARS-CoV-2 and measured key inflammasome activation signals. MDMi …