[PDF][PDF] Induction of pro-inflammatory cytokines (IL-1 and IL-6) and lung inflammation by Coronavirus-19 (COVI-19 or SARS-CoV-2): anti-inflammatory strategies

P Conti, G Ronconi, AL Caraffa… - J Biol Regul Homeost …, 2020 - researchgate.net
… Pro-inflammatory cytokine levels are correlated with CoV-19 replication and disease. It is …
of coronavirus-19 (CoV-19 or SARSCoV-2) infection and lung inflammation mediated by IL-1. J …

The roles of critical pro‐inflammatory cytokines in the drive of cytokine storm during SARSCoV‐2 infection

MS Qudus, M Tian, S Sirajuddin, S Liu… - Journal of Medical …, 2023 - Wiley Online Library
… -inflammatory responses through complex inflammatory networks. Here, we review the
involvements of these critical inflammatory cytokines in SARS-CoV-2 … or regulating cytokine storm, …

… of elevated levels of pro‐inflammatory cytokines in SARSCoV‐infected ACE2+ cells in SARS patients: relation to the acute lung injury and pathogenesis of SARS

L He, Y Ding, Q Zhang, X Che, Y He… - The Journal of …, 2006 - Wiley Online Library
… acute respiratory syndrome (SARS) and that the SARS coronavirus (SARS-CoV) nucleoprotein
is … 2 (ACE2), SARS-CoV spike (S) protein, and some pro-inflammatory cytokines (PICs) …

SARS-CoV-2 infection: The role of cytokines in COVID-19 disease

VJ Costela-Ruiz, R Illescas-Montes… - Cytokine & growth factor …, 2020 - Elsevier
… The key point in SARS-CoV-2 infection could be the depletion of antiviral defenses related
to innate immune response as well as an elevated production of inflammatory cytokines [41]. …

[HTML][HTML] TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines

M Zheng, R Karki, EP Williams, D Yang… - Nature …, 2021 - nature.com
… Given the critical role of TLR2 in SARS-CoV-2 infection-induced inflammatory cytokine … of
mice after infection with SARS-CoV-2. Due to the receptor specificity of SARS-CoV-2, we used …

[HTML][HTML] SARS-CoV-2 causes a different cytokine response compared to other cytokine storm-causing respiratory viruses in severely ill patients

M Olbei, I Hautefort, D Modos, A Treveil… - Frontiers in …, 2021 - frontiersin.org
… Although for a subset of pro-inflammatory cytokines, SARS-CoV-2 does induce a similar
response to the compared viruses, the literature reports conflicting results for a few important …

[HTML][HTML] SARS-CoV-2 infection induces a pro-inflammatory cytokine response through cGAS-STING and NF-κB

CJ Neufeldt, B Cerikan, M Cortese, J Frankish… - Communications …, 2022 - nature.com
… and SARS-CoV-2 infected lung epithelial cells were enriched for pro-inflammatory cytokines
We also demonstrate that SARS-CoV-2 infection leads specifically to NF-κB, but not IRF3 …

[HTML][HTML] Macrophages and dendritic cells are not the major source of pro-inflammatory cytokines upon SARS-CoV-2 infection

MA Niles, P Gogesch, S Kronhart… - Frontiers in …, 2021 - frontiersin.org
… in the production of pro-inflammatory cytokines is still under discussion. Surprisingly, we
could not observe production of pro-inflammatory cytokines by SARS-CoV-2 infected mDC, M1-, …

[HTML][HTML] Exploring the role of immune system and inflammatory cytokines in SARS-CoV-2 induced lung disease: a narrative review

C Tirelli, M De Amici, C Albrici, S Mira, G Nalesso, B Re… - Biology, 2023 - mdpi.com
SARS-CoV-2 infection may induce an over activation of the … -inflammatory cytokines,
leading to a “cytokine storm”, a recognized pathogenetic mechanism in the genesis of SARS-CoV-2-…

Cytokine storm induced by SARS-CoV-2

P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
… NF-κB complex is activated to promote the transcription of inflammatory cytokines; (d) IL-1 and
… of inflammatory cytokines. PRR activates the transcription of multiple cytokines and delays …