Can molecular mimicry explain the cytokine storm of SARSCoV‐2?: An in silico approach

G Obando‐Pereda - Journal of medical virology, 2021 - Wiley Online Library
… the SARS-CoV-2 related cytokine storm by a hyper-inflammatory state as well as by the
MAS. In this manner, this study demonstrated that PARP9 could be depressed by the same …

An interferon‐γ‐related cytokine storm in SARS patients

KJ Huang, IJ Su, M Theron, YC Wu… - Journal of medical …, 2005 - Wiley Online Library
… highly elevated in the acute phase post SARSCoV infection, and were significantly different
… Since SARS-CoV infection can be fatal, and intensive inflammatory response is involved in …

Cytokines and microRNAs in SARS-CoV-2: What do we know?

FZ Rarani, B Rashidi, MHJN Abadi, MR Hamblin… - … Therapy-Nucleic Acids, 2022 - cell.com
… release of pro-inflammatory cytokines in patients suffering from … storm. This review
discusses the cytokines involved in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Challenges and opportunities from targeting inflammatory responses to SARS-CoV-2 infection: a narrative review

V Lariccia, S Magi, T Serfilippi, M Toujani… - Journal of Clinical …, 2020 - mdpi.com
… For instance, molecules that target specific inflammatory pathways would be clinically …
of inflammatory storm caused by SARS-CoV-2 infection. In addition, targeted anti-inflammatory

SARS-CoV-2 triggers inflammatory responses and cell death through caspase-8 activation

S Li, Y Zhang, Z Guan, H Li, M Ye, X Chen… - Signal transduction and …, 2020 - nature.com
… lung damage and inflammatory cytokine storm are believed … whether SARS-CoV-2 infection
induces inflammatory responses … for studying the pathogenesis of SARS-CoV-2. The HFH4-…

[HTML][HTML] NLRP3 inflammasome activation and SARS-CoV-2-mediated hyperinflammation, cytokine storm and neurological syndromes

D Dutta, J Liu, H Xiong - International journal of physiology …, 2022 - ncbi.nlm.nih.gov
… are multifaceted, accumulating evidence indicates that host cells necessitate inflammasome
activation to produce inflammatory cytokines leading to the storm [45,51]. Inflammasomes …

The cytokine storm and COVID‐19

B Hu, S Huang, L Yin - Journal of medical virology, 2021 - Wiley Online Library
… cells, resulting in cytokine storms. Collectively, the impaired acquired immune responses
and uncontrolled inflammatory innate responses to SARS-CoV-2 may cause cytokine storms. …

Before the “cytokine storm”: Boosting efferocytosis as an effective strategy against SARS-CoV-2 infection and associated complications

S Dutta, A Mukherjee, U Nongthomba - Cytokine & Growth Factor Reviews, 2022 - Elsevier
… anti-inflammatory programming. We … storm” which occur concomitantly with the SARS-CoV-2
infection. Finally, we propose how targeting impaired efferocytosis, due to the SARS-CoV-2 …

Inflammation resolution: a dual-pronged approach to averting cytokine storms in COVID-19?

D Panigrahy, MM Gilligan, S Huang, A Gartung… - Cancer and metastasis …, 2020 - Springer
… However, this storm is not a self-limiting, singular event. SARS-CoV-2 causes massive cell
… -derived “eicosanoid storm”, a surge of pro-inflammatory bioactive lipid mediators, such as …

Could SARS-CoV-2-induced hyperinflammation magnify the severity of coronavirus disease (CoViD-19) leading to acute respiratory distress syndrome?

ASS Girija, EM Shankar, M Larsson - Frontiers in immunology, 2020 - frontiersin.org
… systemic cytokine storm (8). Cytokine storm refers to a systemic acute inflammatory manifestation
… Cytokine storm likely could dampen innate and adaptive immune responses against …