Implications of SARS-Cov-2 infection on eNOS and iNOS activity: Consequences for the respiratory and vascular systems

LMF Guimaraes, CVT Rossini, C Lameu - Nitric oxide, 2021 - Elsevier
… process triggered by SARS-CoV-2 infection. The … activity, lowering NO production, causing
pulmonary physiological alterations and coagulopathy. On the other hand, iNOS activity is …

IFN-γ-mediated control of SARS-CoV-2 infection through nitric oxide

BJA Silva, PA Krogstad, RMB Teles… - Frontiers in …, 2023 - frontiersin.org
… By comparing the MFI of DAF-FM and iNOS in cells positive or negative for SARS-CoV-2 …
been shown to induce an antiviral activity against SARS-CoV-2 (18, 28), we compared the …

Oxidative stress‐related mechanisms in SARSCoV‐2 infections

J Wieczfinska, P Kleniewska… - Oxidative medicine and …, 2022 - Wiley Online Library
… (iNOS) expression and activity through the myeloid differentiation primary response-88 (MyD-88)
adapter protein [31]. These processes lead to an increase in the RNS production. The …

[HTML][HTML] Saying no to SARS-CoV-2: the potential of nitric oxide in the treatment of COVID-19 pneumonia

H Zhang, C Zhang, W Hua, J Chen - Medical Gas Research, 2024 - journals.lww.com
… [ 83 ] As is described above, the process of viral infection is always accompanied by the
excessive production of iNOS-derived NO. Whether regulating iNOS activity or using NO …

[HTML][HTML] Potential immunoregulatory and antiviral/SARS-CoV-2 activities of nitric oxide

GB Stefano, T Esch, RM Kream - Medical Science Monitor …, 2020 - ncbi.nlm.nih.gov
… -lived bursts of released NO, whereas iNOS is induced following a … attributed to the local
actions of iNOS, and research has not … mediated by constitutive NO and iNOS, it appears that the …

Dietary foods containing nitric oxide donors can be early curators of SARSCoV‐2 infection: A possible role in the immune system

S Swathi Krishna, A Thennavan… - Journal of food …, 2022 - Wiley Online Library
… cell fusion activity (… SARS-CoV and reduces its fusion activity by inhibiting palmitoylation
and inactivating the cysteine protease (identical to the S2 subunit of spike proteins of SARS-CoV

[HTML][HTML] Inhibition of SARS-coronavirus infection in vitro by S-nitroso-N-acetylpenicillamine, a nitric oxide donor compound

E Keyaerts, L Vijgen, L Chen, P Maes… - International journal of …, 2004 - Elsevier
… Glycyrrhizin upregulates the expression of iNOS and production of NO in macrophages. …
examined the antiviral activity of nitric oxide (NO) against SARS coronavirus (SARS-CoV) isolate …

Pleiotropic effects of nitric oxide on SARS-CoV-2 infections

B Terroni, JR Lopes, CM Chin, JL Dos Santos - Coronaviruses, 2021 - ingentaconnect.com
… The effect of iNOS on the replication of SARS-CoV was also … of SARS and exert an antiviral
activity on the SARS-CoV virus… NO exerting a direct antiviral activity on SARS-CoV-2 (Table 1; …

Dual inhibition of CB1 receptors and iNOS, as a potential novel approach to the pharmacological management of acute and long COVID‐19

R Cinar, MR Iyer, G Kunos - British journal of pharmacology, 2022 - Wiley Online Library
activity of the endocannabinoid/CB 1 receptor system and inducible NO synthase (iNOS). We
Coronavirus disease (COVID-19) caused by the SARS-CoV-2 virus has emerged as a viral …

… of antioxidant, immunomodulatory activity of oxidised Epigallocatechin-3-Gallate (green tea polyphenol) and its action on the main protease of SARS-CoV-2—an in …

R Ungarala, M Munikumar, SN Sinha, D Kumar… - Antioxidants, 2022 - mdpi.com
activity of EGCG has been well documented in the literature due to its ability to scavenge
free radical ions and increase antioxidant enzyme activity … nitric oxide synthase (iNOS), and …