… two vaccine doses and then inoculated with SARS-CoV-2. Those that received the lowest
dose showed signs of controlling the infection, and those receiving the highest dose appeared …

… In two groups of juvenile and adult hamsters infected by intranasal and ocular routes with
SARS-CoV-2 at a higher and lower dose of 105.6 PFU (≈5.68 × 105 TCID50) and 1000 PFU (…

… SARS-CoV-2 from 34 COVID-19 patients. A total of 34 hospitalized patients (admission date
from Feb 1 st to Feb 29 th , 2020) with confirmed SARS-CoV-… guideline for SARS-CoV-2 from …

… drug searching interets for the new coronavirus SARS-CoV-2. Although currently several …
SARS-CoV-2 virus replication and displayed virus entry blocking effect in Vero cells at low dose…

… , we demonstrate that a SAM vaccine encoding SARS-CoV-2 spike induces humoral and …
protection from SARS-CoV-2 replication post-infection at low doses. A SAM-SARS-CoV-2 spike …

… -SARS-CoV-2-S) in challenge studies with severe acute respiratory syndrome coronavirus 2
(SARS-CoV… Intramuscular dosing of ChAd-SARS-CoV-2-S induces robust systemic humoral …

… A low dose intranasal challenge of the same SARS-CoV-2 virus (5×10 2 pfu) appeared to
result in infection of only one ferret which shed viral RNA in the upper respiratory tract and …

… , a low-dosage vaccine challenge would be more likely to start, and start earlier. A low-dosage …
A key ethical advantage of a low-dosage challenge over a conventional challenge is that …

… These data demonstrated that a single low dose of Ad5-nCoV can completely protect both
the upper respiratory tract and lungs of mice from infection and it seemed that the infection …

… dose or two doses of a SARS-CoV-2 vaccine. As with natural immunity, we allow for one- or
two-dose … To reflect the increase in available doses resulting from a delayed second dose, …