Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) dose, infection, and disease outcomes for coronavirus disease 2019 (COVID-19): a review

LM Brosseau, K Escandón, AK Ulrich… - Clinical Infectious …, 2022 - academic.oup.com
… It may be that less severe health outcomes are associated with lower doses, but there are …
that lower dose is associated with less severe health outcomes, being limited by inferring viral …

Low immunization rates among kidney transplant recipients who received 2 doses of the mRNA-1273 SARS-CoV-2 vaccine

I Benotmane, G Gautier-Vargas… - Kidney …, 2021 - kidney-international.org
… rates of KTRs who received 2 doses of the mRNA-1273 SARS-CoV-2 vaccine (Moderna).
3 … history for coronavirus disease 2019 (COVID-19) and tested negative for anti–SARS-CoV-2 …

Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model

TF Rogers, F Zhao, D Huang, N Beutler, A Burns, W He… - Science, 2020 - science.org
… -2 nAbs were delivered at five different concentrations to evaluate dose-… highest dose and
8 μg per animal at the lowest dose. The Den3 control antibody was delivered at a single dose

Syrian hamsters as a small animal model for SARS-CoV-2 infection and countermeasure development

M Imai, K Iwatsuki-Horimoto, M Hatta… - Proceedings of the …, 2020 - National Acad Sciences
… of the dose administered (13). Thus, in the hamster model, SARS-CoV-1 and SARS-CoV-2 …
at a low dose. However, histopathology and body weight changes differ depending on the …

Repeated exposure to subinfectious doses of SARS-CoV-2 May promote T cell immunity and protection against severe COVID-19

ML De Angelis, F Francescangeli, R Rossi, A Giuliani… - Viruses, 2021 - mdpi.com
… In this opinion, we explore the hypothesis that low doses of SARS-CoV-2 present in
populated environments may induce virus-specific T cell responses, leading to progressive …

Favipiravir at high doses has potent antiviral activity in SARS-CoV-2− infected hamsters, whereas hydroxychloroquine lacks activity

SJF Kaptein, S Jacobs, L Langendries… - Proceedings of the …, 2020 - National Acad Sciences
… The oral, low dose used in the current study (300 mg⋅kg −1 ⋅d −1 ) was found to be effective
in viral infection models using hamsters for, among others, Nipah virus, Rift Valley fever …

SARS-CoV-2: a potential trigger for subacute thyroiditis? Insights from a case report

S Ippolito, F Dentali, ML Tanda - Journal of endocrinological investigation, 2020 - Springer
… Of note, naso-pharyngeal control swab test for SARS-CoV-2 resulted positive 2 months after
… by SARS-CoV-2 infection. Neck pain was absent, but the patient was under high doses of …

Third BNT162b2 vaccination neutralization of SARS-CoV-2 Omicron infection

I Nemet, L Kliker, Y Lustig, N Zuckerman… - … England Journal of …, 2022 - Mass Medical Soc
… the BNT162b2 vaccine against wild-type SARS-CoV-2 and the beta, … , we found low
neutralization efficiency with two doses of the … after receipt of the second dose, and no …

Safety and effectiveness of SARSCoV‐2 vaccines: a systematic review and meta‐analysis

Y Ling, J Zhong, J Luo - Journal of medical virology, 2021 - Wiley Online Library
… Phase II data from CanSino's Ad5-vector COVID-19 vaccine showed a GMT of 656.5 (95%
CI: 575.2–749.2) on day 28 after inoculation in the low dose group and GMT of 571.0 (95% CI…

In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains

RE Chen, ES Winkler, JB Case, ID Aziati, TL Bricker… - Nature, 2021 - nature.com
… At the lower doses of the mAbs we tested, we observed some differences in mAb cocktail
efficacy between rodent models, which could be due to host variation, viral variation or small …