… that monocyte-derived macrophages (MDMs) are resistant and unresponsive to SARS-CoV-2
infection. Here, we demonstrate that upon phagocytosis of SARS-CoV-2-infected cells, …

… alveolar epithelial cells (pneumocytes) by SARS-CoV-2 and culminating in the development
… and to alveolar macrophage activation. Activated macrophages secrete proinflammatory …

… macrophages can be used to combat SARS-CoV-2. However, the hyperinflammatory macrophage
… against pathogens; however, using the phagocytosis assay developed for SARS-CoV-…

… that SARS-CoV-2 can complete its life cycle in macrophages. … macrophages were found to
be able to promote SARS-CoV-2 … that the virus infects monocytes and macrophages without …

… , but the virus is … , the macrophage/monocyte responses are central to SARS pathogenesis
(137, 138). It should be noted that, while SARS-CoV-1 infection in mononuclear phagocytes is …

… In conclusion, during the SARS-CoV-2 infection, macrophages seem to have advantageous
and disadvantageous roles. Through phagocytic functions, they remove pathogens and cell …

… or anti-SARS-CoV-2 neutralizing antibodies and phagocytosis-specific phosphatidylserines.
… the virus after containment by Nanotrap-mediated macrophage phagocytosis. The role of …

… SARS coronavirus (SARS-CoV) mouse infection models, immune factors responsible for
clearing of the virus. … -derived infiltrating macrophages and partially alveolar macrophages) play …

… ), is the most ubiquitous signal that triggers their phagocytosis (Fadok et al., 1992; Nagata,
2018). To determine whether phagocytes efficiently engulf SARS- CoV- 2- infected AC (CoV2- …

… 5a), to test whether this enhances phagocytic activity of macrophages. As expected, … hours
before infection with SARS-CoV-2 virus markedly reduced the viral protein (SARS-CoV-2 N …