Molecular basis of SARS-CoV-2 infection and rational design of potential antiviral agents: modeling and simulation approaches

A Frances-Monerris, C Hognon, T Miclot… - Journal of Proteome …, 2020 - ACS Publications
SARS-CoV-2 infection mechanism and the proposal of novel and original agents to inhibit
the viral key functioning. This Review deals with the SARS-CoV-… as the SARS unique domain. …

Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants

M McCallum, AC Walls, KR Sprouse, JE Bowen… - Science, 2021 - science.org
… Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-… acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), the … The SARS-CoV-2 spike (S) glycoprotein is exposed at the …

[HTML][HTML] Broad host range of SARS-CoV-2 and the molecular basis for SARS-CoV-2 binding to cat ACE2

L Wu, Q Chen, K Liu, J Wang, P Han, Y Zhang, Y Hu… - Cell discovery, 2020 - nature.com
… the molecular basis of the cACE2 binding to SARS-CoV-2 RBD, we prepared the SARS-CoV-…
at 3 Å resolution with one SARS-CoV-2 RBD binding to a single cACE2 molecule (Table 1). …

New insights from chemical biology: molecular basis of transmission, diagnosis, and therapy of SARS-CoV-2

Z Zhao, Y Wang, L Qiu, T Fu, Y Yang, R Peng… - CCS …, 2021 - chinesechemsoc.org
… To elucidate the molecular basis for SARS-CoV-2 infectivity and virulent human-to-human …
between SARS-CoV-2 RBD and ACE2. These findings could shed light on the molecular

[HTML][HTML] Unpacking pandora from its box: Deciphering the molecular basis of the SARS-CoV-2 coronavirus

VB O'Leary, OJ Dolly, C Höschl, M Černa… - … Journal of Molecular …, 2020 - mdpi.com
… of this ongoing pandemic, the purpose of this review is to overview the SARS-CoV-2
virus from a molecular perspective with implications for treatment to combat this novel virion. …

[HTML][HTML] Exploiting the molecular basis of age and gender differences in outcomes of SARS-CoV-2 infections

D Mercatelli, E Pedace, P Veltri, FM Giorgi… - Computational and …, 2021 - Elsevier
… Starting from this observation, we investigated the molecular basis of this phenomenon.
Next, we recall that ageing is a heterogeneous process that presents differences among …

[HTML][HTML] The molecular basis for SARS-CoV-2 binding to dog ACE2

Z Zhang, Y Zhang, K Liu, Y Li, Q Lu, Q Wang… - Nature …, 2021 - nature.com
… ), and that both pseudotyped and authentic SARS-CoV-2 can infect dACE2-expressing cells…
a molecular basis for cross-species transmission and potential animal spread of SARS-CoV-…

Molecular basis for ADP-ribose binding to the Mac1 domain of SARS-CoV-2 nsp3

DN Frick, RS Virdi, N Vuksanovic, N Dahal… - Biochemistry, 2020 - ACS Publications
SARS-CoV-2 and the original SARS virus, but several others are not. This study examines
one of the proteins encoded by SARS-CoV… Although 26% of the amino acids in this SARS-CoV

Structural and molecular basis of the interaction mechanism of selected drugs towards multiple targets of SARS-CoV-2 by molecular docking and dynamic simulation …

S Skariyachan, D Gopal, S Chakrabarti… - Computers in biology …, 2020 - Elsevier
… The structural and molecular basis of interactions suggest that the FDA drugs can be
repurposed towards multiple targets of SARS-CoV-2, and the present computational models …

[PDF][PDF] Cross-species recognition and molecular basis of SARS-CoV-2 and SARS-CoV binding to ACE2s of marine animals

S Li, R Yang, D Zhang, P Han, Z Xu… - National Science …, 2022 - academic.oup.com
SARSCoV and SARS-CoV antibodies were detected in masked palm civets (Paguma …
civets indicated that they were clear of SARS-CoV, and SARS-CoV was more likely to have been …