Efficacy and safety of molnupiravir for the treatment of SARS-CoV-2 infection: a systematic review and meta-analysis

JJ Malin, S Weibel, H Gruell… - Journal of …, 2023 - academic.oup.com
… routine use of molnupiravir for COVID-19 treatment in … -19 who were treated with molnupiravir
[absolute risk reduction (… outpatients with risk factors treated with molnupiravir. Moreover, …

Molnupiravir, an oral antiviral treatment for COVID-19

W Fischer, JJ Eron Jr, W Holman, MS Cohen, L Fang… - MedRxiv, 2021 - medrxiv.org
coronavirus (MERS-CoV) virus replication and pathogenesis. In a SARS-CoV-2 ferret model,
molnupiravir treatment … ability of treatment to reduce and eliminate infectious SARS-CoV-2 …

[HTML][HTML] Molnupiravir for oral treatment of Covid-19 in nonhospitalized patients

A Jayk Bernal, MM Gomes da Silva… - … England Journal of …, 2022 - Mass Medical Soc
… the Covid-19 treatment armamentarium. Another advantage of molnupiravir over SARS-CoV-2 …
is the efficacy of molnupiravir against SARS-CoV-2 variants. The mechanism of action of …

[HTML][HTML] The combined treatment of Molnupiravir and Favipiravir results in a potentiation of antiviral efficacy in a SARS-CoV-2 hamster infection model

R Abdelnabi, CS Foo, SJF Kaptein, X Zhang… - …, 2021 - thelancet.com
… of Molnupiravir and Favipiravir in the SARS-CoV-2 … virus titers in the lungs, the combination
causes a >4.5 log 10 reduction of such titers. When start of the combination treatment was …

The preclinical discovery and development of molnupiravir for the treatment of SARS-CoV-2 (COVID-19)

P Pagliano, C Sellitto, T Ascione… - Expert Opinion on …, 2022 - Taylor & Francis
Molnupiravir (MOV) is a broad-spectrum oral antiviral agent approved for the treatment of …
against many RNA viruses such as influenza virus and some alphaviruses agents of epidemic …

Molnupiravir in COVID-19: A systematic review of literature

AK Singh, A Singh, R Singh, A Misra - Diabetes & Metabolic Syndrome …, 2021 - Elsevier
Molnupiravir initially emerged as a possible treatment of … epithelial cell culture against
SARS-CoV-2. Improvement in … infected with SARS-CoV-2 that were administered molnupiravir [6]. …

[HTML][HTML] Molnupiravir—a novel oral anti-SARS-CoV-2 agent

CC Lee, CC Hsieh, WC Ko - Antibiotics, 2021 - mdpi.com
… of SARS-CoV-2 in type-2 pneumocytes [25]. In addition, molnupiravir therapy completely
blocked SARS-CoV-2 … We believe that early molnupiravir treatment in asymptomatic or mildly …

[HTML][HTML] Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis

F Kabinger, C Stiller, J Schmitzová… - Nature structural & …, 2021 - nature.com
… drug candidate for the treatment of patients with COVID-19 is molnupiravir (or EIDD-2801), …
the effects of molnupiravir or NHC on the RNA synthesis activity of SARS-CoV-2 RdRp using …

[HTML][HTML] SARS-CoV-2 Omicron variant is highly sensitive to molnupiravir, nirmatrelvir, and the combination

P Li, Y Wang, M Lavrijsen, MM Lamers, AC de Vries… - Cell research, 2022 - nature.com
molnupiravir and nirmatrelvir for treating Omicron-infected patients. We further call the initiation
of clinical studies to evaluate the combination of molnupiravir and nirmatrelvir for treating

[HTML][HTML] Discovery, development, and patent trends on molnupiravir: a prospective oral treatment for COVID-19

M Imran, M Kumar Arora, SMB Asdaq, SA Khan… - Molecules, 2021 - mdpi.com
… A combination of molnupiravir with favipiravir and other antivirals is also possible due to
their synergistic effects for the treatment of new variants of SARS-CoV-2. At the time of …