Efficacy and safety of molnupiravir for the treatment of SARS-CoV-2 infection: a systematic review and meta-analysis

JJ Malin, S Weibel, H Gruell… - Journal of …, 2023 - academic.oup.com
… Among patients aged 65 and above they found that molnupiravir reduced the risk of …
the use of molnupiravir in hospitalized patients. Wong et al. compared 1856 patients without …

Safety and efficacy of molnupiravir in SARSCoV‐2‐infected patients: A real‐life experience

A De Vito, A Colpani, A Bitti, B Zauli… - Journal of Medical …, 2022 - Wiley Online Library
… of our patients could explain it since the median age in people treated with molnupiravir
in the … Our data support the efficacy of molnupiravir also in older people without SARS-CoV-2 …

Molnupiravir in COVID-19: A systematic review of literature

AK Singh, A Singh, R Singh, A Misra - Diabetes & Metabolic Syndrome …, 2021 - Elsevier
… of molnupiravir in patientsSARS-CoV-2. Improvement in pulmonary function and decline
in viral titer were noted in mice infected with SARS-CoV-2 that were administered molnupiravir […

[HTML][HTML] Molnupiravir—a novel oral anti-SARS-CoV-2 agent

CC Lee, CC Hsieh, WC Ko - Antibiotics, 2021 - mdpi.com
… treatment in asymptomatic or mildly symptomatic patients can potentially prevent viral
transmissions among susceptible individuals because the prophylactic efficacy of oral …

Molnupiravir, an oral antiviral treatment for COVID-19

W Fischer, JJ Eron Jr, W Holman, MS Cohen, L Fang… - MedRxiv, 2021 - medrxiv.org
SARS-CoV-2 in patients with COVID-19. … of molnupiravir to reduce replication of SARS-CoV-2
and accelerate clearance of infectious virus and support ongoing trials of molnupiravir to …

Clinical efficacy and safety of molnupiravir for nonhospitalized and hospitalized patients with COVID‐19: A systematic review and meta‐analysis of randomized control …

PY Huang, TH Liu, JY Wu, YW Tsai… - Journal of Medical …, 2023 - Wiley Online Library
patients, reported that the early addition of molnupiravir to usual … efficacy of molnupiravir in
treating patients with COVID-19. … “coronavirus disease 2019,” “COVID-19,” “SARS coronavirus

Optimal dose and safety of molnupiravir in patients with early SARS-CoV-2: a Phase I, open-label, dose-escalating, randomized controlled study

SH Khoo, R Fitzgerald, T Fletcher… - Journal of …, 2021 - academic.oup.com
… from a study in patients with mild-to-moderate SARS-CoV-2 infection who received 200,
400 or 800 mg of molnupiravir twice daily for 5 days or placebo. Virus was cultured from …

Human safety, tolerability, and pharmacokinetics of molnupiravir, a novel broad-spectrum oral antiviral agent with activity against SARS-CoV-2

WP Painter, W Holman, JA Bush… - Antimicrobial agents …, 2021 - Am Soc Microbiol
Molnupiravir has demonstrated in vitro activity against severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-… Prophylactic and therapeutic administration of molnupiravir to mice …

… of molnupiravir and nirmatrelvir plus ritonavir against mortality, hospitalisation, and in-hospital outcomes among community-dwelling, ambulatory patients with …

CKH Wong, ICH Au, KTK Lau, EHY Lau, BJ Cowling… - The Lancet, 2022 - thelancet.com
Background Little is known about the real-world effectiveness of oral antivirals against the
SARS-CoV-2 omicron (B.1.1.529) variant. We aimed to assess the clinical effectiveness of two …

Randomized trial of molnupiravir or placebo in patients hospitalized with Covid-19

JR Arribas, S Bhagani, SM Lobo, I Khaertynova… - NEJM …, 2022 - evidence.nejm.org
Molnupiravir’s longitudinal impact on SARS-CoV-2 viral load from nasopharyngeal
samples was assessed through real-time polymerase chain reaction (PCR). To evaluate …