… of effective epitopes to be … SARS-CoV-2 infections and experimental validations for the selection of B-, CD4+ and CD8+ T-cell epitopes which could lead to the construction of a multi…
T Kar, U Narsaria, S Basak, D Deb, F Castiglione… - Scientific reports, 2020 - nature.com
… a multi-epitope vaccine using spike glycoprotein of SARS-CoV-… that the designed multi-epitope vaccine is structurally stable … , can be a potential vaccine candidate against SARS-CoV-2. …
… epitope on the top of the spike that included elements of the RBDs from two adjacent S1 protomers (Fig. 4c), consistent with the epitope … 3b to map the epitopes of many of our SARS-CoV…
… against the SARS-CoV-2 spike protein. Hence, in this study, we choose the spike protein sequence of the SARS-CoV-2 as the main subject to design our multi-epitope vaccine. …
K Abraham Peele, T Srihansa… - Journal of …, 2021 - Taylor & Francis
… SARS-CoV-2 is to explore the target structural protein. In the present study, a novel multi-epitope … against the novel Coronavirus. The vaccine candidate was designed using B and T-cell …
… a multi-epitope vaccine against SARS-CoV-2 by utilizing an immunoinformatics approach. For this purpose, we used the SARS-CoV-2 … In this research, a multi-epitope vaccine has been …
… approaches to predict highly antigenic epitopes from SARS-CoV-2 structural proteins that … lymphocyte (HTL) epitopes for construction of vaccine. Thus, the multi-epitopic subunit vaccine …
T Noy-Porat, E Makdasi, R Alcalay, A Mechaly… - Nature …, 2020 - nature.com
… in spite its ability to bind and neutralize SARS-CoV 17 . As opposed to MD29 and MD47, … fully human, SARS-CoV-2 neutralizing antibodies that target four distinct epitopes on the spike …
Y Feng, H Jiang, M Qiu, L Liu, S Zou, Y Li, Q Guo… - Pathogens, 2021 - mdpi.com
… consisting of multiple B-cell and T-cell epitopes of SARS-CoV-2 … Eventually, this multi-epitope-based vaccine managed to elicit … , demonstrating its potential in combating SARS-CoV-2. …