[HTML][HTML] SARS-CoV-2 501Y. V2 variants lack higher infectivity but do have immune escape

Q Li, J Nie, J Wu, L Zhang, R Ding, H Wang, Y Zhang… - Cell, 2021 - cell.com
… Moreover, the neutralization resistance we detected for the … As of early February 2021,
SARS-CoV-2 had infected more … SARS-CoV-2 is a member of the coronavirus family, which …

[HTML][HTML] Neutralization of SARS-CoV-2 Omicron sub-lineages BA. 1, BA. 1.1, and BA. 2

JP Evans, C Zeng, P Qu, J Faraone, YM Zheng… - Cell host & …, 2022 - cell.com
… major variants to neutralizing antibodies from … escape that is largely overcome by mRNA
vaccine booster doses. While Omicron BA.1.1 escapes almost completely from neutralization by …

[HTML][HTML] SARS-CoV-2 Omicron sublineages exhibit distinct antibody escape patterns

H Gruell, K Vanshylla, M Korenkov, P Tober-Lau… - Cell Host & Microbe, 2022 - cell.com
… resistance may therefore favor immune-escape-mediated BA.4/… SARS-CoV-2 neutralizing
potency. Our study provides a detailed understanding of Omicron-sublineage antibody escape

[HTML][HTML] Antibody escape and global spread of SARS-CoV-2 lineage A. 27

T Kaleta, L Kern, SL Hong, M Hölzer, G Kochs… - Nature …, 2022 - nature.com
… Our data demonstrate that A.27 can partially escape the neutralization by sera of vaccinees
and recovered COVID-19 patients, and by therapeutic mAbs. This study emphasizes the …

[HTML][HTML] Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies

AJ Greaney, TN Starr, CO Barnes, Y Weisblum… - Nature …, 2021 - nature.com
… in neutralization also had large effects in our escape maps, although in a few cases mutations
with more moderate effects on neutralization were not prominent in the escape maps (Figs…

[HTML][HTML] A single amino acid substitution in the S1 and S2 Spike protein domains determines the neutralization escape phenotype of SARS-CoV

Y Mitsuki, K Ohnishi, H Takagi, M Oshima… - Microbes and …, 2008 - Elsevier
… efficient neutralization of SARS-CoV infection in … neutralization, we selected
neutralization-escape mutant clones that dominantly grew under the selection pressure of these …

[HTML][HTML] Antibody evasion by SARS-CoV-2 Omicron subvariants BA. 2.12. 1, BA. 4 and BA. 5

Q Wang, Y Guo, S Iketani, MS Nair, Z Li, H Mohri… - Nature, 2022 - nature.com
… mutations within the receptor-binding domain (RBD) of the spike protein raises the spectre
that BA.2.12.1 and BA.4/5 may have evolved to further escape from neutralizing antibodies. …

An antibody-escape estimator for mutations to the SARS-CoV-2 receptor-binding domain

AJ Greaney, TN Starr, JD Bloom - Virus evolution, 2022 - academic.oup.com
… To create an escape map for an antibody mix that more … for thirty-three neutralizing antibodies
elicited by SARS-CoV-2. These … neutralization data from three published studies on SARS-…

Tetravalent SARS-CoV-2 neutralizing antibodies show enhanced potency and resistance to escape mutations

S Miersch, Z Li, R Saberianfar, M Ustav, JB Case… - Journal of molecular …, 2021 - Elsevier
escape mutants, we generated HIV-gag-based, lentivirus-like particles (VLPs) pseudotyped
with the SARS-CoV-… We defined as escape mutants those VLP variants for which entry in the …

SARS-CoV-2 Omicron variant escapes neutralization by vaccinated and convalescent sera and therapeutic monoclonal antibodies

N Ikemura, A Hoshino, Y Higuchi, S Taminishi, T Inaba… - MedRxiv, 2021 - medrxiv.org
escape from vaccine, convalescent sera and therapeutic drugs. Here we analyze the alteration
of their neutralizing … fold lower neutralization titers against Omicron than D614G mutation. …