M Huang, L Wu, A Zheng, Y Xie, Q He, X Rong, P Han… - Immunity, 2022 - cell.com
… neutralize Omicron pseudoviruses. Moreover, to reveal molecular mechanism of immune escape … -1, RBD-5, and RBD-7) with different neutralizing potencies. Our data demonstrate the …
H Tang, L Gao, Z Wu, F Meng, X Zhao, Y Shao… - Frontiers in …, 2022 - frontiersin.org
… and antigenicity of SARS-CoV-2, leading to the immune escape from those neutralizing antibodies. … system was used to assess the infectivity and immune escape. We found that some …
… To functionally confirm that the spike protein mutations detected by sequencing are responsible for the loss of SARS-CoV-2 neutralization by the antibodies, we generated VSV-…
M Li, F Lou, H Fan - Signal Transduction and Targeted Therapy, 2022 - nature.com
… However, the emergence of Omicron variant with high infectivity and immune escape ability … -binding domain (RBD) escaping mutation profile for 247 neutralizing antibodies (NAbs) …
D Tian, Y Sun, J Zhou, Q Ye - Frontiers in immunology, 2021 - frontiersin.org
… Vaccines induce neutralizing antibodies against the SARS-CoV-2 and induce a T cell response against the virus. Animal experiments have shown that a single intramuscular injection …
… data are in accordance with the quantity of significant RBD mutations that provide escape from neutralizing antibodies. In Table 2, the most significant RBD mutations responsible for …
C Sun, YF Kang, YT Liu, XW Kong, HQ Xu… - … and Targeted Therapy, 2022 - nature.com
… neutralizing antibody or receptor with wild-type SARS-CoV-2 … By specifying mutations from different SARS-CoV-2 variants, … immune escape effect in a pseudovirus neutralization assay (…
… that both viral stocks could be neutralized efficiently. These data demonstrate that … SARS-CoV-2 have altered antigenicity. We used a range of high-, medium-, and low-titer neutralizing …
Z Cui, P Liu, N Wang, L Wang, K Fan, Q Zhu, K Wang… - Cell, 2022 - cell.com
… Severe acute respiratory syndrome coronavirus 2 (SARS-CoV… infectivity, and immune escape as observed among emerging … basis for neutralization of SARS-CoV-2 and SARS-CoV by a …