Neutralizing antibody responses elicited by SARS-CoV-2 mRNA vaccination wane over time and are boosted by breakthrough infection

JP Evans, C Zeng, C Carlin, G Lozanski… - Science Translational …, 2022 - science.org
… of future SARS-CoV-2 booster doses. In this study, we examined neutralizing antibody (nAb)
titers in 48 vaccinated health care workers (HCWs) against the major SARS-CoV-2 …

[HTML][HTML] Neutralising antibody titres as predictors of protection against SARS-CoV-2 variants and the impact of boosting: a meta-analysis

D Cromer, M Steain, A Reynaldi, TE Schlub… - The Lancet …, 2022 - thelancet.com
… symptomatic infection with a similar virus. Here we extend that work to show that neutralising
antibodies are also highly predictive of protection from SARS-CoV-2 variants of concern. …

[HTML][HTML] Broadly-neutralizing antibodies against emerging SARS-CoV-2 variants

LB Shrestha, N Tedla, RA Bull - Frontiers in immunology, 2021 - frontiersin.org
… Hence, the neutralizing potency of the … of neutralizing the emerging variants. In this
section we discuss several of these antibodies and describe their interaction with the SARS-CoV-2 …

[HTML][HTML] A therapeutic neutralizing antibody targeting receptor binding domain of SARS-CoV-2 spike protein

C Kim, DK Ryu, J Lee, YI Kim, JM Seo, YG Kim… - Nature …, 2021 - nature.com
… In this study, we demonstrated the potential therapeutic benefit of neutralizing antibody
CT-P59 targeting RBD of SARS-CoV-2 in vitro and in vivo studies. We found that CT-P59 binds to …

[PDF][PDF] Cross-reactive antibody response between SARS-CoV-2 and SARS-CoV infections

H Lv, NC Wu, OTY Tsang, M Yuan, RAPM Perera… - Cell reports, 2020 - cell.com
… the antibody response to SARS-CoV-2 and SARS-CoV infection. … of antibody responses to
SARS-CoV-2 and SARS-CoV in … -neutralizing response to both SARSCoV-2 and SARS-CoV

[PDF][PDF] Rapid decline in vaccine-boosted neutralizing antibodies against SARS-CoV-2 Omicron variant

KE Lyke, RL Atmar, CD Islas, CM Posavad… - Cell Reports …, 2022 - cell.com
coronavirus 2 (SARS-CoV-2) exhibits reduced susceptibility to vaccine-induced neutralizing
antibodies, … We assess the magnitude and short-term durability of neutralizing antibodies

[HTML][HTML] Antibody resistance of SARS-CoV-2 variants B. 1.351 and B. 1.1. 7

P Wang, MS Nair, L Liu, S Iketani, Y Luo, Y Guo… - Nature, 2021 - nature.com
… As for the ramifications of our findings for the protective efficacy of current SARS-CoV-2
vaccines, the neutralizing activity of sera from vaccinated individuals against B.1.1.7 is largely …

Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection

CJ Reynolds, L Swadling, JM Gibbons, C Pade… - Science …, 2020 - science.org
… Our pseudotyped virus neutralization assay has been validated in this study with … SARS-CoV-2
virus neutralization and previously (36). However, while pseudotyped virus neutralization

[PDF][PDF] Human-IgG-neutralizing monoclonal antibodies block the SARS-CoV-2 infection

J Wan, S Xing, L Ding, Y Wang, C Gu, Y Wu, B Rong… - Cell reports, 2020 - cell.com
… the neutralizing abilities of most of the other antibodies. We also find that 515-5 could cross
neutralize the SARS-CoVneutralizing antibodies for COVID-19 as therapeutic candidates. …

[PDF][PDF] A SARS-CoV-2 infection model in mice demonstrates protection by neutralizing antibodies

AO Hassan, JB Case, ES Winkler, LB Thackray… - Cell, 2020 - cell.com
… These data suggest that neutralizing antibodies can protect against SARS-CoV-2-induced
lung inflammation. In summary, we have developed a model of SARS-CoV-2 lung infection …