[HTML][HTML] Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses

KO Saunders, E Lee, R Parks, DR Martinez, D Li… - Nature, 2021 - nature.com
… ) and Middle East respiratory syndrome, as well as the current pandemic of SARS
coronavirus 2 (SARS-CoV-2) 1,2,3,4 . Vaccines that elicit protective immunity against …

Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection

A Gharbharan, CCE Jordans… - Nature …, 2021 - nature.com
… high titers of neutralizing SARS-CoV-2 antibodies, no overall … tract, influence SARS-CoV-2
antibody development or serum … had potent neutralizing SARS-CoV-2 antibodies at hospital …

[HTML][HTML] SARS-CoV-2 variants B. 1.351 and P. 1 escape from neutralizing antibodies

M Hoffmann, P Arora, R Groß, A Seidel, BF Hörnich… - Cell, 2021 - cell.com
… Further, the S protein of SARS-CoV-2 is the main target for neutralizing antibodies, and
several recombinant neutralizing antibodies have been granted Emergency Use Authorization (…

Discovery of ultrapotent broadly neutralizing antibodies from SARS-CoV-2 elite neutralizers

K Vanshylla, C Fan, M Wunsch, N Poopalasingam… - Cell host & …, 2022 - cell.com
… -CoV cross-reactive antibodies as well as a large pool of SARS-CoV-2 broadly neutralizing
antibodies … These bNAbs are ultrapotent against circulating SARS-CoV-2 variants of concern (…

Infection and vaccine-induced neutralizing-antibody responses to the SARS-CoV-2 B. 1.617 variants

VV Edara, BA Pinsky, MS Suthar, L Lai… - … England Journal of …, 2021 - Mass Medical Soc
… located in antigenic sites recognized by antibodies with potent neutralizing activity. We used
serum … to assess neutralizing activity against the SARS-CoV-2 variants in a live-virus assay. …

Human-IgG-neutralizing monoclonal antibodies block the SARS-CoV-2 infection

J Wan, S Xing, L Ding, Y Wang, C Gu, Y Wu, B Rong… - Cell reports, 2020 - cell.com
… the neutralizing abilities of most of the other antibodies. We also find that 515-5 could cross
neutralize the SARS-CoVneutralizing antibodies for COVID-19 as therapeutic candidates. …

Neutralizing antibody activity against 21 SARS-CoV-2 variants in older adults vaccinated with BNT162b2

J Newman, N Thakur, TP Peacock, D Bialy… - Nature …, 2022 - nature.com
… titres fell 4.9-fold to a median titre of 21.3 (neutralization dose 80%), with 21.6% … neutralizing
antibodies at the later time point. Next, we examined neutralization of 21 distinct SARS-CoV-…

Immune evasion of neutralizing antibodies by SARS-CoV-2 Omicron

L Wang, M Møhlenberg, P Wang, H Zhou - Cytokine & growth factor …, 2023 - Elsevier
… of Omicron to evade immunity from neutralizing antibodies, produced by natural infection
and/or … capacity of SARS-CoV-2, with an emphasis on the neutralizing antibodies generated by …

Neutralizing antibody response of vaccinees to SARS-CoV-2 variants

G Anichini, C Terrosi, G Gori Savellini, C Gandolfo… - Vaccines, 2021 - mdpi.com
… functional neutralizing antibodies. The most remarkable finding of this study was the significantly
lower neutralizing antibody titer against B.1.351 lineage, compared to the wild-type virus

A human monoclonal antibody blocking SARS-CoV-2 infection

C Wang, W Li, D Drabek, NMA Okba… - Nature …, 2020 - nature.com
… The emergence of the novel human coronavirus SARS-CoV-2 in Wuhan, China … antibody
that neutralizes SARS-CoV-2 (and SARS-CoV) in cell culture. This cross-neutralizing antibody