… the NLRP3 inflammasome activation. We also show that SARS-CoV-2 N protein promotes
the assembly of the NLRP3 inflammasome through direct interaction with NLRP3 protein. …

… Sars-Cov E protein, regulates the NLRP3 inflammasome. We show in cell culture that the
Sars-Cov… (UPR) and NLRP3 inflammasome priming, leading to reduced NLRP3-dependent …

… with Nlrp3 inflammasome in pathogenesis of SARS-CoV-2 … Nlrp3 inflammasome inhibitors
(eg, the small molecule MCC950), similarly to other compounds proposed to affect SARS-CoV…

… This review tentatively covers the current progress on SARS-CoV-2-induced NLRP3
inflammasome activation, hyperinflammation, cytokine storm, and neurological consequences. We …

… As microglial NLRP3 inflammasome activation is a major driver of neurodegeneration,
here … SARS-CoV-2 can promote microglial NLRP3 inflammasome activation. Using SARS-CoV-2 …

… In conclusion, since we still do not have an effective SARS-CoV-2 vaccine in hand, … Nlrp3
inflammasome by the small-molecule inhibitor MCC950 or application of Nlrp3 inflammasome …

… This NLRP3 over-activated … NLRP3 inflammasome plays a central role in the increased
lethality observed in elderly patients infected by COVID-19. Strategies blocking inflammasome …

… NLRP3 inflammasomes 47 . Our findings indicate the SARS-CoV can activate NLRP3
inflammasome … While SARS-CoV abortively infects macrophages/monocytes, enough ORF8b may …

… dependent on NLRP3 inflammasome activation, which … NLRP3 inflammasome activation
in lung inflammation and fibrosis in both COVID-19 and SARS, and there is evidence of NLRP3 …

… demonstrate that the NLRP3 inflammasome is activated in response to SARS-CoV-2 … NLRP3
inflammasome in PBMCs and tissues of postmortem patients upon autopsy. Inflammasome-…