[HTML][HTML] SARS-CoV-2 viral dynamics in non-human primates

A Gonçalves, P Maisonnasse, F Donati… - PLoS computational …, 2021 - journals.plos.org
… of data generated in non-human primates is a unique … Here, we used data generated on
nonhuman primates (NHP… ] to develop a mathematical model of SARS-CoV-2 infection. Although …

[HTML][HTML] Hydroxychloroquine use against SARS-CoV-2 infection in non-human primates

P Maisonnasse, J Guedj, V Contreras, S Behillil… - Nature, 2020 - nature.com
… emerged as an active compound against SARS-CoV-2 in different … displays in vitro antiviral
activity against SARS-COV-2 5,17 , … set up non-human primate (NHP) models of SARS-CoV-2 …

Comparison of SARS-CoV-2 infections among 3 species of non-human primates

S Lu, Y Zhao, W Yu, Y Yang, J Gao, J Wang, D Kuang… - BioRxiv, 2020 - biorxiv.org
… In this study, two families of non-human primates, Old world monkeys (12 Macaca mulatta, 6
… affect the infection of SARS-CoV-2 in these monkeys. The non-human primate model in this …

Immunogenicity of clinically relevant SARS-CoV-2 vaccines in nonhuman primates and humans

PJ Klasse, DF Nixon, JP Moore - Science advances, 2021 - science.org
… the coronavirus disease 2019 pandemic. The leading candidates have now been evaluated
in nonhuman primates (… with severe acute respiratory syndrome coronavirus 2 in immunized …

Overview of nonhuman primate models of SARS-CoV-2 infection

AM Trichel - Comparative Medicine, 2021 - ingentaconnect.com
… Currently, 6 publications have used the AGM model for SARSCoV-2.Table 1 summarizes
the age, sex, and number of AGM used per study, the virus strain and dose, clinical disease …

[HTML][HTML] Exacerbated innate host response to SARS-CoV in aged non-human primates

SL Smits, A de Lang, JMA van den Brand… - PLoS …, 2010 - journals.plos.org
virus-induced ALI/ARDS in aged individuals are ill-defined. Here, we show that SARS-CoV-infected
aged macaques develop more severe pathology than young adult animals, even …

The gastrointestinal tract is an alternative route for SARS-CoV-2 infection in a nonhuman primate model

L Jiao, H Li, J Xu, M Yang, C Ma, J Li, S Zhao, H Wang… - Gastroenterology, 2021 - Elsevier
nonhuman primate (NHP) model of COVID-19, we sought to elucidate how the GI tract is
involved in SARS-CoV… , that intranasal inoculation with SARS-CoV-2 caused pneumonia and GI …

[HTML][HTML] Neuropathology and virus in brain of SARS-CoV-2 infected non-human primates

I Rutkai, MG Mayer, LM Hellmers, B Ning… - Nature …, 2022 - nature.com
… acute respiratory syndrome coronavirus 2 (SARS-CoV-2) … with SARS-CoV-2 infection in
two non-human primate (NHP) … in SARS-CoV-2 infected NHPs and provides key insights into …

[HTML][HTML] Medical imaging of pulmonary disease in SARS-CoV-2-exposed non-human primates

MA Stammes, JH Lee, L Meijer, T Naninck… - Trends in Molecular …, 2022 - cell.com
… respiratory syndrome coronavirus 2 (SARS-CoV-2)-exposed non-human primates (NHPs) to
… Our review of the literature indicates that medical imaging of SARS-CoV-2-exposed NHPs …

SARS-CoV-2 infection and disease outcomes in non-human primate models: advances and implications

L Yuan, Q Tang, H Zhu, Y Guan… - Emerging Microbes & …, 2021 - Taylor & Francis
SARS-CoV-2 uses to infect humans and cause COVID-19. Several studies demonstrated that
the non-human primate (NHP) is permissive for SARS-CoV-2 … response to SARS-CoV-2, as …