Use of convalescent serum reduces severity of COVID-19 in nonhuman primates

RW Cross, AN Prasad, V Borisevich, C Woolsey… - Cell reports, 2021 - cell.com
… of SARS-CoV-2-infected African green monkeys with convalescent sera containing either high
or low anti-SARS-CoV… AGMs with SARS-CoV-2 and subsequently treated the animals with …

[HTML][HTML] One or two dose regimen of the SARS-CoV-2 synthetic DNA vaccine INO-4800 protects against respiratory tract disease burden in nonhuman primate …

KE Gooch, TRF Smith, FJ Salguero, SA Fotheringham… - Vaccine, 2021 - Elsevier
… In summary, after high dose SARS-CoV-2 challenge of nonhuman primates the disease
burden was reduced in the animals receiving a 1 or 2 dose regimen of INO-4800 vaccine. There …

[HTML][HTML] Global view on virus infection in non-human primates and implications for public health and wildlife conservation

ZJ Liu, XK Qian, MH Hong, JL Zhang, DY Li… - Zoological …, 2021 - ncbi.nlm.nih.gov
… respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly spread worldwide.
Notably, recent studies suggest that pets and other animals may also be infected by SARS-CoV-2 …

Comparative analysis of ACE2 protein expression in rodent, non-human primate, and human respiratory tract at baseline and after injury: A conundrum for COVID-19 …

S Soni, Y Jiang, Y Tesfaigzi, JL Hornick, S Çataltepe - PLoS One, 2021 - journals.plos.org
… severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)… non-human primate (NHP)
models. We also examined ACE2 expression in human tissues with and without coronavirus

SARS-CoV-2 cellular tropism

V Cagno - The Lancet Microbe, 2020 - thelancet.com
… The susceptibility of different cell lines to SARS-CoV and SARS-CoV-… SARS-CoV and
SARS-CoV-2 replicated efficiently, but cytopathic effects were only seen in the non-human primate

Comparative pathogenesis of three human and zoonotic SARS-CoV strains in cynomolgus macaques

B Rockx, F Feldmann, D Brining, D Gardner… - PLoS …, 2011 - journals.plos.org
… In this study we compare the pathogenesis of three recombinant SARS-CoV isolates … Urbani
SARS-CoV from our molecular clone have previously been tested in a non-human primate

ACE2 and TMPRSS2 variation in savanna monkeys (Chlorocebus spp.): Potential risk for zoonotic/anthroponotic transmission of SARS-CoV-2 and a potential …

CA Schmitt, CM Bergey, AJ Jasinska, V Ramensky… - PLoS …, 2020 - journals.plos.org
… Aspects of the biology of SARS-CoV-2 infection call for … non-human primates kept as pets,
among wild non-human … human, non-human primates and selected domestic animals showed …

A single intranasal dose of chimpanzee adenovirus-vectored vaccine protects against SARS-CoV-2 infection in rhesus macaques

AO Hassan, F Feldmann, H Zhao, DT Curiel… - Cell Reports …, 2021 - cell.com
… in non-human primates. Rhesus macaques were immunized with ChAd-Control or ChAd-SARS-CoV-2-S …
and intrabronchial routes with SARS-CoV-2. A single intranasal dose of ChAd-…

[HTML][HTML] Rapid protection from COVID-19 in nonhuman primates vaccinated intramuscularly but not intranasally with a single dose of a recombinant vaccine

W Furuyama, K Shifflett, AN Pinski, AJ Griffin… - BioRxiv, 2021 - ncbi.nlm.nih.gov
… syndrome coronavirus 2 (SARS CoV-2). … SARS CoV-2. Here, we generated a single dose,
fast-acting vesicular stomatitis virus-based vaccine derived from the licensed Ebola virus (…

Animal models for SARSCoV‐2 research: a comprehensive literature review

K Pandey, A Acharya, M Mohan, CL Ng… - Transboundary and …, 2021 - Wiley Online Library
SARS-CoV-2 in NHPs. A recent study by Bao et. al. used the non-human primate models
with SARS-CoV-2 infection followed by a repeat challenge with the same virus to ascertain the …