Lack of evidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spillover in free-living neotropical non-human primates, Brazil

L Sacchetto, BA Chaves, ER Costa… - Viruses, 2021 - mdpi.com
… to be susceptible to experimental infection with SARS-CoV-2. Together, these findings …
SARS-CoV-2. To assess the potential exposure of free-living non-human primates to SARS-CoV-2…

An Alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates

JH Erasmus, AP Khandhar, MA O'Connor… - Science translational …, 2020 - science.org
… of SARS-CoV-2 S–targeted DNA and live viral vector vaccines tested in nonhuman primates
(53, 58)… In addition, the ability of our repRNA vaccine to induce anti–SARS-CoV-2 S–specific …

Synthetic multiantigen MVA vaccine COH04S1 protects against SARS-CoV-2 in Syrian hamsters and non-human primates

F Chiuppesi, VH Nguyen, Y Park, H Contreras… - npj Vaccines, 2022 - nature.com
… modified vaccinia Ankara-based SARS-CoV-2 vaccine that co-… SARS-CoV-2 challenge.
Moreover, we demonstrate that single-dose or two-dose vaccination of non-human primates with …

Low-dose self-amplifying mRNA COVID-19 vaccine drives strong protective immunity in non-human primates against SARS-CoV-2 infection

AR Rappaport, SJ Hong, CD Scallan, L Gitlin… - Nature …, 2022 - nature.com
… for assessing non-human primate sera. We thank Battelle Memorial Institute for execution
of the non-human primate challenge study and performing the live virus microneutralization …

[PDF][PDF] Hydroxychloroquine in the treatment and prophylaxis of SARS-CoV-2 infection in non-human primates

P Maisonnasse, J Guedj, V Contreras, S Behillil… - Research …, 2020 - academia.edu
… Based on previous studies of SARS-COV and MERS-COV infection, we and others have
set up experimental models of non-human primates (NHP) infected with SARS-CoV-2 that …

A pan-sarbecovirus vaccine induces highly potent and durable neutralizing antibody responses in non-human primates against SARS-CoV-2 Omicron variant

Z Liu, JFW Chan, J Zhou, M Wang, Q Wang, G Zhang… - Cell research, 2022 - nature.com
SARS-CoV-2 WA1 strain and its 9 variants (Alpha, Beta, Gamma, Delta, Epsilon, Zeta, Eta,
Iota and Kappa), SARS-CoV and SARS-… to elicit nAbs in non-human primates (NHPs) and …

[PDF][PDF] A recombinant receptor-binding domain in trimeric form generates protective immunity against SARS-CoV-2 infection in nonhuman primates

L Yang, D Tian, J Han, W Fan, Y Zhang, Y Li, W Sun… - The Innovation, 2021 - cell.com
… These results demonstrated that the SARS-CoV-2 RBD trimer … immunity protection in nonhuman
primates, thereby offering an … SARS-CoV-2 infection in vaccinated nonhuman primates (…

Nonhuman primate models for evaluation of SARS-CoV-2 vaccines

JA Neil, M Griffith, DI Godfrey, DFJ Purcell… - Expert Review of …, 2022 - Taylor & Francis
… for the study of SARS-CoV and MERS-CoV, such as nonhuman primates (NHPs), ferrets, …
of potential SARS-CoV-2 vaccine candidates. For example, SARS-CoV and MERS-CoV mouse …

[HTML][HTML] Recombinant SARS-CoV-2 spike S1-Fc fusion protein induced high levels of neutralizing responses in nonhuman primates

W Ren, H Sun, GF Gao, J Chen, S Sun, R Zhao, G Gao… - Vaccine, 2020 - Elsevier
The COVID-19 outbreak has become a global pandemic responsible for over 2,000,000
confirmed cases and over 126,000 deaths worldwide. In this study, we examined the …

Interaction dynamics between innate and adaptive immune cells responding to SARS-CoV-2 vaccination in non-human primates

CA Schramm, D Moon, L Peyton, NS Lima… - Nature …, 2023 - nature.com
… As SARS-CoV-2 variants continue evolving, testing updated vaccines in non-human primates
remains important for guiding human clinical practice. To date, such studies have focused …