[HTML][HTML] … SARS-CoV-2 spike protein and AS03 adjuvant induces rapid anamnestic antibodies in the lung and protects against virus challenge in nonhuman primates

JR Francica, BJ Flynn, KE Foulds, AT Noe, AP Werner… - BioRxiv, 2021 - ncbi.nlm.nih.gov
… GlaxoSmithKline was evaluated for its ability to protect nonhuman primates against SARS-CoV-2
challenge in advance of clinical trials. Although SARS-CoV-2 mRNA- and adenovirus-…

[PDF][PDF] A pathogen-like antigen-based vaccine confers immune protection against SARS-CoV-2 in non-human primates

C Guo, Y Peng, L Lin, X Pan, M Fang, Y Zhao… - Cell Reports …, 2021 - cell.com
… ) of the SARS-CoV-2 S … in non-human primates (NHPs) and found that it could also induce
neutralizing antibodies and, most importantly, accelerate the viral clearance upon SARS-CoV-…

Adjuvanting a subunit SARS-CoV-2 nanoparticle vaccine to induce protective immunity in non-human primates

PS Arunachalam, AC Walls, N Golden, C Atyeo… - bioRxiv, 2021 - biorxiv.org
… immunity against SARS-CoV-2 in non-human primates. … effective subunit vaccine against
SARS-CoV-2 would represent an … for use in candidate subunit SARS-CoV-2 vaccines; however, …

Single-dose replicating RNA vaccine induces neutralizing antibodies against SARS-CoV-2 in nonhuman primates

JH Erasmus, AP Khandhar, AC Walls, EA Hemann… - bioRxiv, 2020 - biorxiv.org
… We show that intramuscular injection of LION/repRNA-CoV2S elicits robust anti-SARS-CoV-2 …
in nonhuman primates elicited antibody responses that potently neutralized SARS-CoV-2. …

A pan-sarbecovirus vaccine based on RBD of SARS-CoV-2 original strain elicits potent neutralizing antibodies against XBB in non-human primates

Z Liu, J Zhou, X Wang, W Xu, Z Teng… - Proceedings of the …, 2023 - National Acad Sciences
… carry many mutations that result in the low- or noneffectiveness of the Alum/RBD-Fc and
the first-generation COVID-19 vaccines, our results suggest that RBD of the original SARS-CoV-…

[HTML][HTML] Soluble spike DNA vaccine provides long-term protective immunity against SARS-CoV-2 in mice and nonhuman primates

YB Seo, YS Suh, JI Ryu, H Jang, H Oh, BS Koo… - Vaccines, 2021 - mdpi.com
nonhuman primatesnonhuman primates were challenged at 10 weeks after the last
vaccination with GX-19, they had reduced viral loads in contrast to non-vaccinated primates as a …

Immune correlates of protection by mRNA-1273 immunization against SARS-CoV-2 infection in nonhuman primates

KS Corbett, MC Nason, B Flach, M Gagne, S O'Connell… - BioRxiv, 2021 - biorxiv.org
… The nonhuman primate (NHP) model of SARS-CoV-2 … vaccine encoding the prefusion-stabilized
SARS-CoV-2 spike (S-2P) … following SARS-CoV-2 challenge in vaccinated animals and …

[HTML][HTML] Intestinal immunological events of acute and resolved SARS-CoV-2 infection in non-human primates

S Hua, K Latha, R Marlin, K Benmeziane, L Bossevot… - Mucosal …, 2024 - Elsevier
… By using a non-human primate (NHP) model of SARS-CoV-2 respiratory infection this study
aimed to analyze the related intestinal immune cell changes and to assess whether these …

[HTML][HTML] Mucosal administration of a live attenuated recombinant COVID-19 vaccine protects nonhuman primates from SARS-CoV-2

MF Tioni, R Jordan, AS Pena, A Garg, D Wu, SI Phan… - npj Vaccines, 2022 - nature.com
… were replaced with a chimeric SARS-CoV-2 spike harboring the cytoplasmic tail of the
RSV F protein. MV-014-212 was attenuated and immunogenic in nonhuman primates (NHPs), …

[HTML][HTML] … and protective efficacy of a recombinant protein subunit vaccine and an inactivated vaccine against SARS-CoV-2 variants in non-human primates

Q He, Q Mao, X Peng, Z He, S Lu, J Zhang… - … and Targeted Therapy, 2022 - nature.com
… clinical trials, intervention experiments with non-human primates (NHPs) are appropriate
for … against SARS-CoV-2 infection are still obscured. Challenging macaque with SARS-CoV-2 …