Immunogenicity and safety of a 3-dose regimen of a SARS-CoV-2 inactivated vaccine in adults: A randomized, double-blind, placebo-controlled phase 2 trial

J Liu, B Huang, G Li, X Chang, Y Liu… - The Journal of …, 2022 - academic.oup.com
… Some studies also demonstrated that a booster dose (third dose) elicited … dose [14].
Here we report the immunogenicity and safety of a 3-dose regimen of an inactivated SARS-CoV-2 …

Safety and immunogenicity of an inactivated SARS-CoV-2 vaccine, BBV152: a double-blind, randomised, phase 1 trial

R Ella, KM Vadrevu, H Jogdand, S Prasad… - The Lancet Infectious …, 2021 - thelancet.com
… However, to the best of our knowledge, ours is the only … safety set includes all participants
who received one dose of the vaccine (n=375). Dose 1 events are from days 0–7 and dose 2 …

Defining the risk of SARS-CoV-2 variants on immune protection

MM DeGrace, E Ghedin, MB Frieman, F Krammer… - Nature, 2022 - nature.com
… To obtain the best experience, we recommend you use a more up to date browser (or turn
off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we …

Effect of an inactivated vaccine against SARS-CoV-2 on safety and immunogenicity outcomes: interim analysis of 2 randomized clinical trials

S Xia, K Duan, Y Zhang, D Zhao, H Zhang, Z Xie, X Li… - Jama, 2020 - jamanetwork.com
safety outcomes 28 days and immunogenicity outcomes 14 days after 3 doses in a phase 1
trial and 2 doses in … June 16, 2020, and recommended that the preliminary analysis report be …

SARS-CoV-2 vaccines strategies: a comprehensive review of phase 3 candidates

NC Kyriakidis, A López-Cortés, EV González… - npj Vaccines, 2021 - nature.com
… To obtain the best experience, we recommend you use a … received two intramuscular doses
2 weeks apart and the safety and … correlates of protection against COVID-19 or SARS-CoV-2 …

Pharmacokinetics and safety of XAV-19, a swine glyco-humanized polyclonal anti-SARS-CoV-2 antibody, for COVID-19-related moderate pneumonia: a randomized …

B Gaborit, E Dailly, B Vanhove, R Josien… - Antimicrobial Agents …, 2021 - Am Soc Microbiol
… and safety of XAV-19, a … coronavirus 2 (SARS-CoV-2), in coronavirus disease 2019 (COVID-19)-related
moderate pneumonia. The objective was to evaluate the optimal dose and safety

Safety and efficacy of the mRNA BNT162b2 vaccine against SARS-CoV-2 in five groups of immunocompromised patients and healthy controls in a prospective open …

P Bergman, O Blennow, L Hansson, S Mielke… - …, 2021 - thelancet.com
… trial evaluating the safety and humoral immune responses following two doses of COVID-19 …
Administration of two consecutive doses, 3 weeks apart, of BNT162b2 was overall safe. The …

Safety and immunogenicity of SARS-CoV-2 recombinant protein vaccine formulations in healthy adults: a randomised, placebo-controlled, dose-ranging study

PA Goepfert, B Fu, AL Chabanon, MI Bonaparte… - medRxiv, 2021 - medrxiv.org
… Our findings indicate that, while the best performing candidate vaccine formulation among
… and dose needed to ensure optimal immune responses, including in those most at risk. …

[HTML][HTML] The feasibility, safety, and efficacy of Paxlovid treatment in SARS-CoV-2-infected children aged 6–14 years: a cohort study

G Yan, J Zhou, H Zhu, Y Chen, Y Lu… - Annals of …, 2022 - ncbi.nlm.nih.gov
… 1 dose of an inactivated SARS-CoV-2 … the safety and efficacy of Paxlovid in children.
Secondly, the blood concentration levels of Paxlovid were not tested, therefore the optimal dosage

… antiviral activity and projection of optimized dosing design of hydroxychloroquine for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

X Yao, F Ye, M Zhang, C Cui, B Huang… - Clinical infectious …, 2020 - academic.oup.com
dose of 200 mg given twice daily for 4 days is recommended for … well as its more tolerable
safety profile in comparison to chloroquine… drug for the treatment of SARS-CoV-2 infection [24]. …