The SARS-CoV-2 main protease (3CLpro) is one of the promising therapeutic targets for the
treatment of COVID-19. Nirmatrelvir is the first 3CLpro inhibitor authorized for treatment of …

… Female sex hormones can only partially explain this protection against SARS-CoV-2 infection.
An important role can certainly be attributed to the X chromosome and, in particular, to the …

… SARS-CoV-2 infection is mild in the majority of individuals … The increased susceptibility
to severe disease in the elderly … tool for reducing susceptibility to and severity of SARS-CoV-2. …

… to infection, at least in the mouse, and that differences in RECON multistate design
explain only partially differences in species susceptibility to SARS‐CoV‐2 infection. …

… In the first scenario, we assume that SARS-CoV-2 has the same sensitivity to climate as
influenza, based on a prior model from laboratory studies (9, 12). In the second and third …

… In contrast with other respiratory viruses, children infected with SARS-CoV-2 are largely …
TMPRSS2 and furin are key proteases involved in SARS-CoV-2 spike protein cleavage. …

… susceptibility to SARS-CoV-2, while other domestic species including pigs and poultry do not
appear susceptible. … to assess the likelihood of SARS-CoV-2 susceptibility in animal hosts. …

… SARS-CoV-2 variants of concern exhibit varying degrees of transmissibility and, in some …
dynamics of wild-type and variant strains of SARS-CoV-2 in the context of vaccine rollout and …

… 4A), we assume that infections of all classes of partially susceptible individuals lead to strong
selective pressures and low viral abundance (a marker of low transmission) and thus low …

… The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein acquired
… more susceptible to neutralization. The G614 pseudovirus also was more susceptible to …