[HTML][HTML] Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies

RE Chen, X Zhang, JB Case, ES Winkler, Y Liu… - Nature medicine, 2021 - nature.com
… introduced antibody and vaccine countermeasures. Here, using monoclonal antibodies (…
, we report the impact on antibody neutralization of a panel of authentic SARS-CoV-2 variants …

[HTML][HTML] High genetic barrier to SARS-CoV-2 polyclonal neutralizing antibody escape

F Schmidt, Y Weisblum, M Rutkowska, D Poston… - Nature, 2021 - nature.com
… by polyclonal antibodies in individuals who are SARS-CoV-2 … with vesicular stomatitis
virus/SARS-CoV-2 chimaeras 5 , here … , are variably targeted by human polyclonal antibodies. …

[HTML][HTML] SARS-CoV-2 variants show resistance to neutralization by many monoclonal and serum-derived polyclonal antibodies

M Diamond, R Chen, X Xie, J Case, X Zhang… - Research …, 2021 - ncbi.nlm.nih.gov
… Here, using monoclonal antibodies (mAbs), animal immune … on antibody neutralization of a
panel of authentic SARS-CoV-2 … We also noted that cell line selection used for growth of virus

[HTML][HTML] Could mutations of SARS-CoV-2 suppress diagnostic detection?

CA Ascoli - Nature biotechnology, 2021 - nature.com
… documented benefits of polyclonal antibodies in applications … In terms of the emerging
SARS-CoV-2 strains — N501Y in … polyclonal antibodies to N protein to detect SARS-CoV-2. Even …

[HTML][HTML] Mutational escape from the polyclonal antibody response to SARS-CoV-2 infection is largely shaped by a single class of antibodies

AJ Greaney, TN Starr, CO Barnes, Y Weisblum… - BioRxiv, 2021 - ncbi.nlm.nih.gov
… -targeting polyclonal response by a single antibody class is a major factor in enabling a small
number of viral mutations to sometimes substantially erode neutralizing antibody immunity. …

[HTML][HTML] Structures of human antibodies bound to SARS-CoV-2 spike reveal common epitopes and recurrent features of antibodies

CO Barnes, AP West, KE Huey-Tubman… - Cell, 2020 - cell.com
… of polyclonal plasma Fabs, revealing recognition of both S1 A and RBD epitopes on SARS-CoV-2
SARS-CoV-2 spike mutations. Overall, our studies structurally define a recurrent anti-…

[HTML][HTML] Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies

AJ Greaney, TN Starr, CO Barnes, Y Weisblum… - Nature …, 2021 - nature.com
… A substantial fraction of the neutralizing activity of polyclonal antibody response to SARS-CoV-2
infection is due to antibodies that target the RBD 17,18,19,20,21 , although …

High neutralizing potency of swine glyco‐humanized polyclonal antibodies against SARSCoV‐2

B Vanhove, O Duvaux, J Rousse… - European Journal of …, 2021 - Wiley Online Library
… Heterologous polyclonal antibodies might represent an … or monoclonal antibodies (mAbs)
in coronavirus disease (… , heterologous antibodies trigger human natural xenogeneic antibody

[HTML][HTML] Reaction of human monoclonal antibodies to SARS-CoV-2 proteins with tissue antigens: implications for autoimmune diseases

A Vojdani, E Vojdani, D Kharrazian - Frontiers in Immunology, 2021 - frontiersin.org
… immune reactivity of human monoclonal antibody made against SARS-CoV-2 spike protein
and nucleoprotein and rabbit polyclonal antibody made against SARS-CoV-2 envelope and …

Antibody detection of SARS-CoV spike and nucleocapsid protein

MS Chang, YT Lu, ST Ho, CC Wu, TY Wei… - Biochemical and …, 2004 - Elsevier
… In this study, we found two peptide-induced antibodies against spike protein and polyclonal
antibodies against nucleocapsid protein could specifically recognize SARS-CoV infected …