Potential inhibitors of SARS-CoV-2: recent advances

G Jamalipour Soufi, S Iravani - Journal of Drug Targeting, 2021 - Taylor & Francis
… -spectrum antiviral agents and strategies against SARS-CoV-2 and future pathogenic viruses.
… the potential inhibitors, antiviral drugs and nanomaterials screened against SARS-CoV-2. …

[HTML][HTML] Structural basis of potential inhibitors targeting SARS-CoV-2 main protease

HM Mengist, T Dilnessa, T Jin - Frontiers in Chemistry, 2021 - frontiersin.org
… achieved in searching for drugs inhibiting the M pro , … potential inhibitors targeting SARS-CoV-2
M pro , identifies gaps, and provides future directions. Further, compounds with potential

Molecular dynamics simulation approach for discovering potential inhibitors against SARS-CoV-2: A structural review

S Ghahremanian, MM Rashidi, K Raeisi… - Journal of molecular …, 2022 - Elsevier
inhibitors of COVID-19 protease, there is a demand to conduct a comprehensive review of the
most important studies to reveal and compare the potential … for adjusting antiviral inhibitors, …

Computational determination of potential inhibitors of SARS-CoV-2 main protease

ST Ngo, N Quynh Anh Pham, L Thi Le… - Journal of chemical …, 2020 - ACS Publications
… We also found that Glu166 forms H-bonds to all of the inhibitors. Replacing … to SARS-CoV-2
Mpro. Our results could contribute to the development of potential drugs inhibiting SARS-CoV

Potential inhibitors for the novel coronavirus (SARS-CoV-2)

Y Han, Z Wang, J Ren, Z Wei, J Li - Briefings in Bioinformatics, 2021 - academic.oup.com
SARS-CoV-2 after intravenous treatment [12], while Chloroquine and Hydroxychloroquine
are being reported to be potential inhibitors of SARS-CoV-2 … its efficacy against SARS-CoV-2. …

[HTML][HTML] In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replication

F Touret, M Gilles, K Barral, A Nougairède… - Scientific reports, 2020 - nature.com
inhibitors, antiarrhythmic agents or CNS drugs emerged showing antiviral potency with 2 <
EC50 ≤ 20 µM. By providing new information on molecules inhibiting SARS-CoV-… SARS-CoV-…

An investigation into the identification of potential inhibitors of SARS-CoV-2 main protease using molecular docking study

S Das, S Sarmah, S Lyndem… - Journal of Biomolecular …, 2021 - Taylor & Francis
… The inhibition of the SARS-CoV-2 main protease is necessary … to identify the possible
inhibitors of the SARS-CoV-2 main … bind to the active site of the SARS-CoV-2 protease (PDB: …

Rapid identification of potential inhibitors of SARSCoV‐2 main protease by deep docking of 1.3 billion compounds

AT Ton, F Gentile, M Hsing, F Ban… - Molecular …, 2020 - Wiley Online Library
… molecule therapeutics for SARS-CoV-2. Along these efforts, the structure of SARS-CoV-2
main … ZINC15 library to identify top 1,000 potential ligands for SARS-CoV-2 Mpro protein. The …

[HTML][HTML] Phytocompounds as potential inhibitors of SARS-CoV-2 Mpro and PLpro through computational studies

M Rudrapal, I Celik, S Chinnam, MA Ansari… - Saudi Journal of …, 2022 - Elsevier
… -7-glucoside-4′-neohesperidoside as potential inhibitors of Mpro and PLpro, respectively.
Other studies have also reported rutin as SARS-CoV-2 Mpro inhibitor (Huynh et al., 2020, …

[HTML][HTML] In-silico design of a potential inhibitor of SARS-CoV-2 S protein

G Jaiswal, V Kumar - PLoS One, 2020 - journals.plos.org
… Its genome is about 82% identical to the SARS coronavirus (SARS-CoV). Specifically…
Potentially, it can block the binding of RBD to ACE2 and hence it can be used as a potential inhibitor