Potential therapeutic targets and promising drugs for combating SARSCoV‐2

H Zhou, Y Fang, T Xu, WJ Ni, AZ Shen… - British Journal of …, 2020 - Wiley Online Library
… μM, while SARS-CoV-2-HR1P exhibited no obvious fusion inhibitory activity up to 40 μM,
indicating that SARS-CoV-2-HR2P may be a promising therapeutic agent for SARS-CoV-2. …

Repurposing therapeutic agents against SARS-CoV-2 infection: most promising and neoteric progress

MJ Hossain, SMA Rahman - … Review of Anti-Infective Therapy, 2021 - Taylor & Francis
… In this review, we summarize the most promising therapeutic … progress reports on these
promising repurposed options through the … insights against the SARS-CoV-2 infection ( Figure 1 ). …

Interfering with host proteases in SARS-CoV-2 entry as a promising therapeutic strategy

P Müller, H Maus, SJ Hammerschmidt… - Current Medicinal …, 2022 - ingentaconnect.com
… Hence, inhibition of these proteases could be a promising strategy for treatment against
SARSCoV-2. In this review, we discuss the current state of the art of developing inhibitors …

Targeting RNA G‐quadruplex in SARSCoV‐2: A promising therapeutic target for COVID‐19?

C Zhao, G Qin, J Niu, Z Wang, C Wang… - Angewandte …, 2021 - Wiley Online Library
… To date, small molecule drug therapy by targeting SARS-CoV… G4s have been identified as
promising therapeutic targets. … G4 might be a promising therapeutic target of SARS-CoV-2. …

Potential antiviral drugs for SARS-Cov-2 treatment: preclinical findings and ongoing clinical research

S Bimonte, A Crispo, A Amore, E Celentano, A Cuomo… - in vivo, 2020 - iv.iiarjournals.org
SARS-Cov-2. Different preclinical in vitro and in vivo studies on other CoVs genetically very
close to SARS-Cov-2 suggested that promising … the rhesus macaque therapeutic remdesivir …

Bee products as a source of promising therapeutic and chemoprophylaxis strategies against COVID‐19 (SARSCoV‐2)

WG Lima, JCM Brito… - Phytotherapy …, 2021 - Wiley Online Library
… Apitherapy is a promising source of … therapeutic effects associated with several bee
products that might be useful in the fight against the pandemic of the novel coronavirus (SARS-CoV-2…

Repurposing therapeutics for potential treatment of SARS-CoV-2: a review

J Santos, S Brierley, MJ Gandhi, MA Cohen… - Viruses, 2020 - mdpi.com
… (SARS-CoV, MERS-CoV, and SARS-CoV-2). Mechanistic and in vitro analyses suggest
multiple promising therapeutic … that therapies with evidence for benefit in SARS-CoV and MERS-…

Promising Therapeutic Approach for SARSCoV‐2 Infections by Using a Rutin‐Based Combination Therapy

M Mazik - ChemMedChem, 2022 - Wiley Online Library
… effects of the other components on the course of SARS-CoV-2 infections, and, last but not …
simple combination therapy a promising and attractive therapeutic approach for SARS-CoV-2 …

[HTML][HTML] Current coronavirus (SARS-CoV-2) epidemiological, diagnostic and therapeutic approaches: An updated review until June 2020

A Nabil, K Uto, MM Elshemy, R Soliman… - EXCLI …, 2020 - ncbi.nlm.nih.gov
… No proven effective therapies or vaccines for SARS-CoV-2 currently exist. The most promising
therapy up till now maybe Remdesivir, also we recommend Corticosteroids therapy for …

A review of SARS-CoV-2 and the ongoing clinical trials

YF Tu, CS Chien, AA Yarmishyn, YY Lin… - International journal of …, 2020 - mdpi.com
… On the other hand, the repurposing of the existing therapeutic … The initial clinical studies
revealed the promising therapeutic … Here, we summarize the ongoing therapeutic options that …