[HTML][HTML] In situ detection of SARS-CoV-2 in lungs and airways of patients with COVID-19

IM Schaefer, RF Padera, IH Solomon, S Kanjilal… - Modern Pathology, 2020 - Elsevier
… of respiratory failure), SARS-CoV-2 was detected in pulmonary pneumocytes and ciliated …
demonstrate the greatest value for SARS IHC when testing lung tissues from patients in the …

Pathological post‐mortem findings in lungs infected with SARSCoV‐2

S Damiani, M Fiorentino, A De Palma… - The Journal of …, 2021 - Wiley Online Library
… We found in the lung tissues of all patients histological changes consistent with diffuse …
pulmonary findings in nine autopsy patients with different clinical courses of SARS-CoV-2-…

[HTML][HTML] Pathological evidence for residual SARS-CoV-2 in pulmonary tissues of a ready-for-discharge patient

XH Yao, ZC He, TY Li, HR Zhang, Y Wang, H Mou… - Cell research, 2020 - nature.com
… Regardless of the negative detection of SARS-CoV-2 virus nucleic acid from … there were
SARS-CoV-2 viruses remaining in the patient. We performed digital PCR on tissue sections from …

The pathophysiology of SARS-CoV-2: A suggested model and therapeutic approach

G Morris, CC Bortolasci, BK Puri, L Olive, W Marx… - Life sciences, 2020 - Elsevier
Pulmonary activated platelets are also an important source of proinflammatory cytokines
and ROS, as well as exacerbating pulmonary … cells into inflamed pulmonary tissue, thereby …

[HTML][HTML] Temporal and spatial heterogeneity of host response to SARS-CoV-2 pulmonary infection

N Desai, A Neyaz, A Szabolcs, AR Shih… - Nature …, 2020 - nature.com
… Our findings highlight the importance in serially assessing tissue pulmonary SARS-CoV-2
RNA levels and the immune response as well as attempt to identify corresponding surrogate …

Antibody responses to SARS-CoV-2 short-lived

N Vabret - Nature Reviews Immunology, 2020 - nature.com
tissues from 11 patients who died of COVID-19, Dorward et al. report that, despite a wide
distribution of viral products in pulmonary and extra-pulmonary tissues, … of SARS-CoV-2 tissue- …

[HTML][HTML] Pathology and pathogenesis of SARS-CoV-2 associated with fatal coronavirus disease, United States

RB Martines, JM Ritter, E Matkovic, J Gary… - Emerging infectious …, 2020 - ncbi.nlm.nih.gov
… Immunostaining of severe acute respiratory syndrome coronavirus 2 in pulmonary tissues
from fatal coronavirus disease cases. A) Patient no. 5: scattered immunostaining of tracheal …

Histologic pulmonary lesions of SARS-CoV-2 in 4 nonhuman primate species: an institutional comparative review

CS Clancy, C Shaia, V Munster, E de Wit… - Veterinary …, 2022 - journals.sagepub.com
… is classically thought to cause disseminated pulmonary disease. Our studies … pulmonary
tissue did not develop lesions, and foci of severe pneumonia were only in a fraction of the tissue

Exploring the pathogenesis of severe acute respiratory syndrome (SARS): the tissue distribution of the coronavirus (SARSCoV) and its putative receptor, angiotensin …

KF To, AWI Lo - The Journal of Pathology: A Journal of the …, 2004 - Wiley Online Library
coronavirus, SARS-CoV. Pulmonary involvement is the dominant clinical feature but extra-…
Studies of the tissue and cellular distribution of SARS-CoV, and ACE2 protein expression, …

[HTML][HTML] Upregulation of pulmonary tissue factor, loss of thrombomodulin and immunothrombosis in SARS-CoV-2 infection

IMB Francischetti, K Toomer, Y Zhang, J Jani… - …, 2021 - thelancet.com
… Coagulation dysregulation has multifactorial etiology in SARS-Cov-2 infection.
Upregulation of pulmonary TF with loss of thrombomodulin emerge as a potential link to …