… past the time when SARS-CoV-2 is an urgent threat. Quaternary ammonium compounds (QACs)
are known to be effective at inactivating enveloped viruses, (1,2) such as SARS-CoV-2, …

… San Francisco, CA), which mimics the N-terminal autocleavage site of the SARS-CoV
main protease and cuts at the Gln↓Ser site ( 22, 23). The peptide substrate was dissolved in …

… quaternary epitope located at the interface between the N-terminal domain and subdomain
1, uncovering a site of vulnerability on SARS-CoV-… scanning showed that SARS-CoV-2 could …

… function of the SARS-CoV Mpro protein. Particular attention is paid to the quaternary structure
of … However, unlike chymotrypsin, the active site of SARS-CoV Mpro contains a catalytic …

… of the coronavirus which is responsible of the severe acute respiratory syndrome (SARS)
have been recently predicted. Here a molecular assembly of SARS coronavirus peplomer …

… against SARS-CoV-2 have been adopted worldwide to limit its spread. Because SARS-CoV-…
best against SARS-CoV-2, especially when it comes to quaternary ammonium compounds (…

… the site without … coronavirus 2 (SARS-CoV-2) 1 , the cause of coronavirus disease 2019
(COVID-19) 2 , highlights our extreme vulnerability to novel pathogens. The speed of SARS-CoV-…

… site and any other possible glycan sites. In comparison, monomeric RBD displayed very high
occupancy of the T323 site, … this site is due to a lack of steric hindrance from the quaternary …

… terminal self-cleavage sites are the two most active substrates for SARS 3C-like proteinase
… In summary, after the completion of the genome sequencing for SARS coronavirus in early …

… We hypothesized that quaternary ammonium antimicrobial, an agent that is able to … that
would render SARS-CoV-2 non-infectious. To investigate the efficacy of quaternary ammonium …