[HTML][HTML] Respiratory disease in rhesus macaques inoculated with SARS-CoV-2

VJ Munster, F Feldmann, BN Williamson… - Nature, 2020 - nature.com
rhesus macaques with the SARS-CoV-2 isolate nCoV-WA1-2020 14 . On day 1 post-inoculation
(dpi), all macaques … Coughing was occasionally heard in the room where macaques

[HTML][HTML] Correlates of protection against SARS-CoV-2 in rhesus macaques

K McMahan, J Yu, NB Mercado, C Loos, LH Tostanoski… - Nature, 2021 - nature.com
… We previously reported that nine rhesus macaques infected with SARS-CoV-2 by the …
rechallenge with SARS-CoV-2 1 . Following rechallenge, these macaques developed increased …

[HTML][HTML] Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2

BN Williamson, F Feldmann, B Schwarz… - Nature, 2020 - nature.com
… of SARS-CoV-2 7,8 . Here we investigate the efficacy of remdesivir in a rhesus macaque
model of SARS-CoV-2 infection 9 . Unlike vehicle-treated animals, macaques treated with …

SARS-CoV-2 infection protects against rechallenge in rhesus macaques

A Chandrashekar, J Liu, AJ Martinot, K McMahan… - Science, 2020 - science.org
SARS-CoV-2 infection in rhesus macaques induced humoral and cellular immune responses
and provided protective efficacy against SARS-CoV… and treatment of SARS-CoV-2 infection …

[HTML][HTML] BNT162b vaccines protect rhesus macaques from SARS-CoV-2

AB Vogel, I Kanevsky, Y Che, KA Swanson, A Muik… - Nature, 2021 - nature.com
… -immunized, SARS-CoV-2 challenged macaques at any of the time points we sampled. …
-old male-macaque challenge model is primarily a model of SARS-CoV-2 infection rather a …

Reinfection could not occur in SARS-CoV-2 infected rhesus macaques

L Bao, W Deng, H Gao, C Xiao, J Liu, J Xue, Q Lv, J Liu… - BioRxiv, 2020 - biorxiv.org
… of rhesus macaques from the reinfection by SARS-CoV-2. Our results indicated that primary
SARS-CoV-2 … antibodies against SARS-CoV-2 might protect rhesus macaques which have …

Primary exposure to SARS-CoV-2 protects against reinfection in rhesus macaques

W Deng, L Bao, J Liu, C Xiao, J Liu, J Xue, Q Lv, F Qi… - Science, 2020 - science.org
… Taken together, our results suggest that rhesus macaques that have undergone an initial
infection with SARS-CoV-2 mount protection against rechallenge during the early recovery days…

[HTML][HTML] Comparison of rhesus and cynomolgus macaques as an infection model for COVID-19

FJ Salguero, AD White, GS Slack… - Nature …, 2021 - nature.com
… For SARS-CoV-1, though rhesus macaques became the preferred species, yet the
literature suggests there is no significant difference in susceptibility of cynomolgus (Macaca …

[HTML][HTML] Responses to acute infection with SARS-CoV-2 in the lungs of rhesus macaques, baboons and marmosets

DK Singh, B Singh, SR Ganatra, M Gazi, J Cole… - Nature …, 2021 - nature.com
… understanding of the NHP models of SARS-CoV-2 infection 1,… , we expanded on the rhesus
macaque model of SARS-CoV-2 … SARS-CoV-2 infection in three NHP genera: Indian rhesus

[HTML][HTML] Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques

NB Mercado, R Zahn, F Wegmann, C Loos… - Nature, 2020 - nature.com
… development of a SARS-CoV-2 vaccine … SARS-CoV-2 spike (S) protein, and evaluated their
immunogenicity and protective efficacy against SARS-CoV-2 challenge in rhesus macaques