Clearance and persistence of SARSCoV‐2 RNA in patients with COVID‐19

A Carmo, J Pereira‐Vaz, V Mota… - Journal of medical …, 2020 - Wiley Online Library
… Mild illness patients maintained viral RNA for a longer period of time … SARS-CoV-2 did not
elicit an effective immune response, explaining the need of more time to viral RNA clearance. …

A phase 2a clinical trial of molnupiravir in patients with COVID-19 shows accelerated SARS-CoV-2 RNA clearance and elimination of infectious virus

WA Fischer, JJ Eron Jr, W Holman, MS Cohen… - Science translational …, 2021 - science.org
clearance of SARS-CoV-2 RNA (primary endpoints), as well as reduce infectious SARS-CoV-2
in nasopharyngeal swabs (secondary endpoint) in adults with symptomatic SARS-CoV-2 …

[HTML][HTML] Estimate and determinants of SARS-CoV-2 RNA clearance time among non-severe COVID-19 patients

MA Aljunaid, AM Albeshry, NZ Alshahrani… - Journal of Family …, 2022 - journals.lww.com
… and negative conversion of Sars-CoV-2 RNA detection in … the factors associated with
prolonged viral RNA shedding.[ 10 11 … the time of Sars-CoV-2 RNA clearance among biologically …

Determinants of prolonged viral RNA shedding in hospitalized patients with SARS-CoV-2 infection

FC Dezza, A Oliva, F Cancelli, G Savelloni… - … and infectious disease, 2021 - Elsevier
… Nevertheless, further studies are needed to understand the immunological mechanisms
involved in the SARS-CoV-2 viral clearance and to reveal how blocking IL-6 receptor is …

Factors associated with prolonged viral RNA shedding in patients with coronavirus disease 2019 (COVID-19)

K Xu, Y Chen, J Yuan, P Yi, C Ding… - Clinical infectious …, 2020 - academic.oup.com
… viral RNA clearance, prolonged SARS-CoV-2 RNA shedding … evaluate the occurrence of
viral RNA clearance in the first 21 … viral RNA clearance, (2) viral RNA clearance occurred within …

SARS-CoV-2 viral clearance and evolution varies by type and severity of immunodeficiency

Y Li, MC Choudhary, J Regan, J Boucau… - Science translational …, 2024 - science.org
… Propensity score matching for delayed versus early viral RNA clearance We defined
delayed viral RNA clearance as clearance of SARS-CoV-2 viral RNA beyond day 30 or positive …

[HTML][HTML] … coronavirus disease 2019 (COVID-19) patients with early clearance and prolonged shedding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Y Zhou, F Ding, W Bao, Y Xue, L Han… - Annals of …, 2021 - ncbi.nlm.nih.gov
SARS-CoV-2 RNA will need a longer time of viral RNA shedding. Here, we aim to determine
the persistence and clearance time of SARS-CoV-2 RNA … of SARS-CoV-2 RNA in a large …

The kinetics of SARS-CoV-2 antibody development is associated with clearance of RNAemia

C Wang, Y Li, P Kaplonek, M Gentili, S Fischinger… - Mbio, 2022 - Am Soc Microbiol
RNA levels from day 7 as a surrogate for viral clearance, we also noted a significant association
between death and day 7 RNA … failure of prompt SARS-CoV-2 RNAemia clearance is an …

[HTML][HTML] Effect of corticosteroid therapy on the duration of SARS-CoV-2 clearance in patients with mild COVID-19: a retrospective cohort study

C Ding, X Feng, Y Chen, J Yuan, P Yi, Y Li, Q Ni… - Infectious diseases and …, 2020 - Springer
… Another study reported that corticosteroid therapy in patients with MERS was not associated
with mortality but was associated with delayed coronavirus RNA clearance [14]. Since there …

Adaptive immune determinants of viral clearance and protection in mouse models of SARS-CoV-2

B Israelow, T Mao, J Klein, E Song, B Menasche… - Science …, 2021 - science.org
SARS-CoV-2 by plaque assay and reduction of viral RNA by … played a minimal role in
clearing SARS-CoV-2 during acute … are insufficient to clear acute SARS-CoV-2 infection. These …