Efficacy and safety of molnupiravir for the treatment of SARS-CoV-2 infection: a systematic review and meta-analysis

JJ Malin, S Weibel, H Gruell… - Journal of …, 2023 - academic.oup.com
molnupiravir has no effect on mortality, probably none on ‘hospitalization or death’ and effects
on symptom resolution are uncertain. Molnupiravir was safe … use of molnupiravir for COVID…

Human safety, tolerability, and pharmacokinetics of molnupiravir, a novel broad-spectrum oral antiviral agent with activity against SARS-CoV-2

WP Painter, W Holman, JA Bush… - Antimicrobial agents …, 2021 - Am Soc Microbiol
molnupiravir was generally safe at the dose levels and duration tested in this study cohort.
Homogeneity in body mass index and other enrollment restrictions that minimize metabolic …

Safety and efficacy of molnupiravir in SARSCoV‐2‐infected patients: A real‐life experience

A De Vito, A Colpani, A Bitti, B Zauli… - Journal of Medical …, 2022 - Wiley Online Library
… of molnupiravir also in older people without SARS-CoV-2 vaccination. Regarding safety, in
… 0.6%), 19 thus confirming the high tolerability and safety of monlupiravir in clinical practice. …

Optimal dose and safety of molnupiravir in patients with early SARS-CoV-2: a Phase I, open-label, dose-escalating, randomized controlled study

SH Khoo, R Fitzgerald, T Fletcher… - Journal of …, 2021 - academic.oup.com
… ) we evaluated the safety and optimal dose of molnupiravir in … the safety and tolerability of
molnupiravir in SARS-CoV-2 … a dose of 800 mg of molnupiravir twice daily is safe and well-…

[HTML][HTML] Efficacy and safety of Molnupiravir in COVID-19 patients: A systematic review

KR Mali, M Eerike, GM Raj, D Bisoi… - Irish Journal of Medical …, 2023 - Springer
… drugs received emergency use authorization (EUA) by the US-FDA for COVID-19 including
the combination of nirmatrelvir and ritonavir, Molnupiravir, and anti-SARS CoV-2 antibodies. …

[HTML][HTML] Efficacy and safety of molnupiravir for COVID-19 patients

M Fatima, S Azeem, J Saeed, A Shahid… - European Journal of …, 2022 - ncbi.nlm.nih.gov
… viral entry into the cell, inhibiting SARS-CoV2 RNA, inhibiting viral … Molnupiravir, an oral
RdRp inhibitor exhibiting … Several trials of molnupiravir have been in COVID-19 patients but …

Molnupiravir in COVID-19: A systematic review of literature

AK Singh, A Singh, R Singh, A Misra - Diabetes & Metabolic Syndrome …, 2021 - Elsevier
… and safety of molnupiravirSARS-CoV-2. Improvement in pulmonary function and decline
in viral titer were noted in mice infected with SARS-CoV-2 that were administered molnupiravir […

[HTML][HTML] Molnupiravir—a novel oral anti-SARS-CoV-2 agent

CC Lee, CC Hsieh, WC Ko - Antibiotics, 2021 - mdpi.com
… In summary, these studies indicate that oral molnupiravir is highly effective in reducing
nasopharyngeal SARS-CoV-2 and offers a favorable tolerability and safety profile. However, we …

[HTML][HTML] Safety profile of molnupiravir in the treatment of COVID-19: A descriptive study based on FAERS data

G Santi Laurini, N Montanaro, D Motola - Journal of Clinical Medicine, 2022 - mdpi.com
… As new variants of SARS-CoV-2 continue to emerge, molnupiravir is expected to be an …
safety surveillance survey was unable to establish a causal relationship between molnupiravir

Human safety, tolerability, and pharmacokinetics of a novel broad-spectrum oral antiviral compound, molnupiravir, with activity against SARS-CoV-2

WP Painter, W Holman, JA Bush, F Almazedi, H Malik… - medrxiv, 2020 - medrxiv.org
… : (i) to determine the safety and tolerability of single and multiple ascending doses of
molnupiravir, and (ii) to assess the effect of food on the pharmacokinetics of molnupiravir and EIDD-…