Safety and Effectiveness of Molnupiravir in Japanese Patients with COVID-19: Final Report of Post-Marketing Surveillance in Japan

S Shinozaki, A Watanabe, M Kimata… - Infectious Diseases and …, 2024 - Springer
… The primary aim of this PMS was to confirm the safety of molnupiravir in Japanese patients
with infection caused by SARS-CoV-2 as early as possible after approval, and secondarily to …

Phase 2/3 trial of molnupiravir for treatment of Covid-19 in nonhospitalized adults

Y Caraco, GE Crofoot, PA Moncada… - NEJM …, 2022 - evidence.nejm.org
safety, efficacy, and virology data from the phase 2, dose-finding component of a trial evaluating
molnupiravir for … Molnupiravir maintains antiviral activity against SARS-CoV-2 variants in …

Antiviral activity of molnupiravir against COVID-19: a schematic review of evidences

S Singla, S Goyal - Bulletin of the National Research Centre, 2022 - Springer
molnupiravir and its active form against highly pathogenic SARS-CoV-2, the pathogen
responsible for COVID-19, and finding out the efficacy and safety of molnupiravir in clinical trials. …

Molnupiravir and nirmatrelvir-ritonavir: oral coronavirus disease 2019 antiviral drugs

LD Saravolatz, S Depcinski… - Clinical Infectious …, 2023 - academic.oup.com
… The molnupiravir group was associated with declines in SARS-CoV-2 RNA levels in …
The safety of molnupiravir was evaluated based on an analysis of a phase 3 double-blind …

[HTML][HTML] Efficacy of Molnupiravir for the treatment of mild or moderate COVID-19 in adults: a meta-analysis

K Benaicha, RR Khenhrani, M Veer, S Devi… - Cureus, 2023 - ncbi.nlm.nih.gov
… inhibit the replication of SARS-CoV-2. A significant advantage of molnupiravir is its favorable
… studies have shown the effectiveness and safety of molnupiravir as an antiviral therapy [23]. …

[HTML][HTML] Molnupiravir—a step toward orally bioavailable therapies for Covid-19

R Whitley - New England Journal of Medicine, 2022 - Mass Medical Soc
… of two phase 2 trials of molnupiravir. Second, the safety database is small and will
require … The UK summary report on molnupiravir recommends licensure for SARS-CoV-2–infected …

[HTML][HTML] Current status of oral antiviral drug treatments for SARS-CoV-2 infection in non-hospitalized patients

DV Parums - … science monitor: international medical journal of …, 2022 - ncbi.nlm.nih.gov
safety of molnupiravir given within five days after the onset of signs or symptoms in unvaccinated
and non-hospitalized adults with mild or moderate SARS-CoV-2 … mg of molnupiravir as …

Molnupiravir: A new candidate for COVID‐19 treatment

F Pourkarim, S Pourtaghi‐Anvarian… - Pharmacology …, 2022 - Wiley Online Library
… evidence about the safety and efficacy of the molnupiravir administration in the … Molnupiravir
inhibits the RdRp enzyme of SARS-CoV-2, and causes several errors in the RNA virus

The benefits of molnupiravir treatment in healthcare facilities patients with COVID-19

SL Cheng, PH Wang, CY Chang… - Drug Design …, 2023 - Taylor & Francis
… , molnupiravir (MOL), a new orally active RdRp inhibitor with a excellent pharmacokinetic
character, has demonstrated to have its ability to interfere SARS-COV-… and safety using MOL in …

[PDF][PDF] Safety monitoring of molnupiravir for treatment of mild to moderate COVID-19 infection in low and middle-income countries using cohort event monitoring: a …

World Health Organization - 2022 - apps.who.int
… , a novel broad-spectrum oral antiviral agent with activity against SARS-CoV-2. Antimicrob
… Optimal dose and safety of molnupiravir in patients with early SARS-CoV2: a Phase I, open-…