In silico bioprospecting of taraxerol as a main protease inhibitor of SARS-CoV-2 to develop therapy against COVID-19

S Mujwar, RK Harwansh - Structural Chemistry, 2022 - Springer
COVID-19 was caused by a novel coronavirus known as SARS-CoV-2. The COVID-19
disease outbreak has been avowed as a global pandemic by the World Health Organization at …

In silico bioprospecting of antiviral compounds from marine fungi and mushroom for rapid development of nutraceuticals against SARS-CoV-2

AK Srivastav, J Jaiswal, U Kumar - Journal of Biomolecular …, 2023 - Taylor & Francis
… alternative drug against SARS-CoV-2 virus with minimum side effects. Though our in silico
studies of these compounds are showing a promising results against SARS-CoV-2 main …

Computational bioprospecting guggulsterone against ADP ribose phosphatase of SARS-CoV-2

M Kciuk, S Mujwar, I Rani, K Munjal, A Gielecińska… - Molecules, 2022 - mdpi.com
… leads for possible inhibitors of the SARS-CoV-2 ADP Ribose … In silico screening has proven
to be a highly effective, … with therapeutic effectiveness against SARS-CoV-2 ARP enzyme. …

Natural products as potential leads against coronaviruses: could they be encouraging structural models against SARS-CoV-2?

IE Orhan, FS Senol Deniz - Natural products and bioprospecting, 2020 - Springer
… investigated for their probable effect against SARS-CoV-2 using in silico techniques [39]. …
from several databases were applied in silico against SARS-CoV PL pro and 3CL pro inhibition…

Recognition of natural products as potential inhibitors of COVID-19 main protease (Mpro): In-silico evidences

RR Narkhede, AV Pise, RS Cheke… - … and Bioprospecting, 2020 - Springer
… activity against SARS coronavirus 3C-like protease [36] and anti-HBV (hepatitis B virus)
activity [37]. … SARS-coronavirus, influenza, foot-and-mouth disease, human immunodeficiency …

Bioprospecting phytochemicals of Rosmarinus officinalis L. for targeting SARS-CoV-2 main protease (Mpro): a computational study

U Patel, K Desai, RC Dabhi, JJ Maru… - Journal of Molecular …, 2023 - Springer
… structure-based drug designs using SARS-CoV-2 crystalline protein structures available …
SARS-CoV-2 infection is to inhibit the activity of S-glycoprotein, as it restricts the latching of virus

Bioprospecting for anti-COVID-19 interventions from African medicinal plants: A review

AJ Akindele, A Sowemimo… - Natural Product …, 2022 - journals.sagepub.com
… Plants and their phytoconstituents that have been reported to be active against SARS CoV in
… A: Evaluation of effect on the replication of HSV using in vitro and in silico approaches; MTT …

Natural products as potential lead compounds for drug discovery against SARS-CoV-2

OT Ebob, SB Babiaka, F Ntie-Kang - Natural products and bioprospecting, 2021 - Springer
… In silico studies have shown that 17 binds with high affinity to … by SARS-CoV-2 to cause
COVID-19 (Fig. 6), suggesting that this compound could be a potential inhibitor of coronavirus

Harnessing and bioprospecting botanical-based herbal medicines against potential drug targets for COVID-19: a review coupled molecular docking studies

T Pal, U Anand, S Sikdar Mitra, P Biswas… - Journal of …, 2023 - Taylor & Francis
SARS-CoV-2 and SARS-CoV. Therefore, the methodologies employed earlier to disrupt the
binding of MERS or SARS-CoV … in silico as possible inhibitors of the major protease of SARS-…

Plant metabolites as SARS-CoV-2 inhibitors candidates: In silico and in vitro studies

AJO Lopes, GP Calado, YN Fróes, SA Araújo… - Pharmaceuticals, 2022 - mdpi.com
bioprospecting and molecular docking as alternative tools for the search of efficient compounds
to combat COVID-19 [7,11,12,13]. The in silico … In silico techniques achieve success in …