… Defining domain geometry and arrangements in SARS-CoV-2 spike To characterize the
unique arrangement of distinct domains in the different β-CoV spikes, we first developed a …

… of SARS-CoV-2 has resulted in >90,000 infections and >3,000 deaths. Coronavirus spike (S)
glycoproteins … We show that SARS-CoV-2 S uses ACE2 to enter cells and that the receptor-…

… of SARS-CoV-2 S glycoprotein, the SARS-CoV-2 RBD retains strong binding affinity to the
SARS-CoV … Recent studies of the pre-fusion SARS-CoV-2 S glycoprotein 30,31 and the …

… SARS-CoV spike (S) protein on the surface of cells, but in its incorporation into lentiviral
particles that can be used to transduce cells in an S glycoprotein-… by SARS-CoV S glycoprotein …

… acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viruses have mutant spike glycoproteins
that … The spike glycoproteins of coronaviruses are responsible for receptor binding and …

… the SARS-CoV-2 genome encodes spike (S) glycoproteins, which protrude from the surface
of mature virions. The S glycoprotein … Surface location of the S glycoprotein renders it a direct …

The envelope spike (S) proteins of MERS-CoV and SARS-CoV determine the virus host
tropism and entry into host cells, and constitute a promising target for the development of …

… of complete SARS-CoV and MERS-CoV spike trimers in pre-… -CoV or HKU4 onto the SARS-CoV
S glycoprotein trimer also … in the SARS-CoV spike would also occur in the spikes of other …

… of the SARS-CoV S glycoprotein in complex … glycoprotein binds ACE2 and adopts a
protruding “up” conformation. In addition, we studied the structures of the SARS-CoV S glycoprotein …

… -CoVs, closely related to SARS-CoV-2, bind strongly to … We also report the cryo-EM structure
of a Pangolin-CoV spike … the spike of a bat coronavirus RaTG13 more than that of SARS-…