Y Yang, L Du - Signal transduction and targeted therapy, 2021 - nature.com
… SARS-CoV-2 spike (S) protein is a key target for eliciting neutralizing antibodies. a Schematic structures of SARS-CoV-2 virion and its S protein. M, … b Mode of action of SARS-CoV-2 S-…
F Tian, B Tong, L Sun, S Shi, B Zheng, Z Wang, X Dong… - elife, 2021 - elifesciences.org
… Envelope-anchored spikeproteins are capable of mediating coronavirus entry into host cells … The coronavirusspikeprotein, a class I fusion protein, is synthesized as a precursor single …
M Sanda, L Morrison, R Goldman - Analytical chemistry, 2021 - ACS Publications
… of the spikeprotein at R682, a polybasic cleavage site that differs from … SARS-CoVspike protein of 2002. By analysis of the protein produced in HEK293 cells, we observe that the spike …
S Laha, J Chakraborty, S Das, SK Manna… - Infection, genetics and …, 2020 - Elsevier
… We have identified frequently mutated residues by aligning ~660 SARS-CoV-… protein structure stability of spike glycoprotein and their possible functional consequences in other proteins. …
AW Struck, M Axmann, S Pfefferle, C Drosten, B Meyer - Antiviral research, 2012 - Elsevier
… by SARScoronavirus (SARS-CoV) is blocked by hexapeptide Tyr-Lys-Tyr-Arg-Tyr-Leu. The peptide also inhibits proliferation of coronavirus … ) of the spikeprotein of SARS-CoV. Peptide …
… The S protein of SARS-CoV-2, which contains 1,273 amino acids, forms a trimeric spike on … We analyzed the SARS-CoV-2 S protein amino acid sequence from viral genomic sequences …
… four antibodies to the spikeprotein that potently neutralize SARS-CoV-2, individually as well … against spike variants that have arisen in the human population. However, novel spike …
… SARS-CoV-2 infects cells via its spikeprotein binding to its … the spikeprotein, or administer recombinant spikeprotein, … , while others showed that the spikeprotein could damage the …
… Belouzard S., Chu VC & Whittaker GR Activation of the SARScoronavirusspikeprotein via sequential proteolytic cleavage at two distinct sites. Proceedings of the National Academy of …