Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors

RN Kirchdoerfer, AB Ward - Nature communications, 2019 - nature.com
… as SARS- and MERS-CoV … -structural proteins (nsp) responsible for the replication and
transcription of the viral genome. Here, we present the 3.1 Å resolution structure of the SARS-CoV

Structural basis of SARS-CoV-2 and SARS-CoV antibody interactions

E Gavor, YK Choong, SY Er, H Sivaraman… - Trends in …, 2020 - cell.com
… acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and SARS-CoV, and discuss …
rampant SARS-CoV-2 infections. We provide a perspective on the mechanisms of SARS-CoV-2-…

Molecular insights into the differential dynamics of SARS-CoV-2 variants of concern

N Mandal, AK Padhi, SL Rath - Journal of Molecular Graphics and …, 2022 - Elsevier
… of SARS-CoV-2 since the first incidence of the Coronavirus disease 2019 (COVID-19) [8,9]. …
molecular insights into the VOCs and would prove crucial for understanding the structure-…

Structural basis of mismatch recognition by a SARS-CoV-2 proofreading enzyme

C Liu, W Shi, ST Becker, DG Schatz, B Liu, Y Yang - Science, 2021 - science.org
structures of both wild-type and mutant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-…
The structures reveal the molecular determinants of ExoN substrate specificity and …

The interplay of SARS-CoV-2 evolution and constraints imposed by the structure and functionality of its proteins

L Jaroszewski, M Iyer, A Alisoltani… - PLoS computational …, 2021 - journals.plos.org
… The unprecedented pace of the sequencing of the SARS-CoV-2 virus genomes provides us
… the SARS-CoV-2 virus mutations along its genome are closely correlated with the structural

[HTML][HTML] Computational insights into the membrane fusion mechanism of SARS-CoV-2 at the cellular level

J Wang, F Maschietto, MJ Guberman-Pfeffer… - … and Structural …, 2021 - Elsevier
… crown-like trimeric spike glycoproteins of SARS-CoV-2 to the receptor angiotensin II… structural
models of super-complexes of spike trimer/ACE2 dimers based on the molecular structures

[HTML][HTML] Crystal structure of SARS-CoV-2 papain-like protease

X Gao, B Qin, P Chen, K Zhu, P Hou, JA Wojdyla… - … Pharmaceutica Sinica B, 2021 - Elsevier
… the crystal structure of the unliganded SARS-CoV-2 … insight of substrate binding mechanism,
we superimposed the unliganded SARS-CoV-2 PLpro structure to an inhibitor bound SARS

Structure of SARS-CoV-2 M protein in lipid nanodiscs

KA Dolan, M Dutta, DM Kern, A Kotecha, GA Voth… - Elife, 2022 - elifesciences.org
… through interactions with other SARS- CoV- 2 structural proteins and perhaps negatively …
during review of this work includes two structures of SARSCoV- 2 M solubilized in detergent …

Insights into SARS-CoV transcription and replication from the structure of the nsp7–nsp8 hexadecamer

Y Zhai, F Sun, X Li, H Pang, X Xu, M Bartlam… - Nature structural & …, 2005 - nature.com
… We present here the crystal structure of the hexadecameric nsp7–nsp8 … SARS-CoV at 2.4-Å
resolution. To our knowledge, it is the first structure to show interactions between coronavirus

Structural insights of the SARS-CoV-2 nucleocapsid protein: implications for the inner-workings of rapid antigen tests

MA Casasanta, GM Jonaid, L Kaylor… - Microscopy and …, 2023 - academic.oup.com
SARS-CoV-2 and a key analyte for lateral-flow rapid antigen tests. Here, we present new
structural insights for the SARS-CoV-… Epitope mapping based on structural data supported host-…