… Virus identical to SARS-CoV-2 in full-genome sequences was isolated from the … to
SARS-CoV-2 could protect mice from severe pneumonia. Our results show that the hACE2 mouse …

… transgenic mouse model for SARS coronavirus. We describe the method by which the hACE2
gene was introduced into the mouse … susceptible to SARS-CoV than were wild-type mice, …

… -hACE2 mice are resistant to SARS-CoV-2. … mouse is suitable for highly susceptible model
of SARS-CoV-2, and CAG-hACE2 mouse is suitable for mild susceptible model of SARS-CoV-…

… that the absence of SARS-CoV-2 + labeling in MVA-S-vaccinated mice was due to a low …
detection limit, we performed highly sensitive RT–qPCR of the SARS-CoV-2 E gene in the …

… susceptible to SARS-CoV-2 infection are needed. In the present study, we established an
animal model highly susceptible to SARS-CoV-… enzyme 2–transgenic (CAG-hACE2) mice. The …

… Although our transgenic mouse model may not fully capture the complexity and diversity of
… reflect the reality of SARS-CoV-2 infection in humans, our hACE2-Tg mouse serves as an in …

… Herein we demonstrate that K18 hACE2 transgenic mice are highly susceptible to SARS-CoV-2
infection, quickly reaching study endpoints by 6-DPI following in infection with 10 5 PFU. …

… In conclusion, our findings indicated the susceptibility of a readily available hamster model
to SARS-CoV-2 infection. Golden Syrian hamsters showed high viral loads in the upper and …

… In this study, we extended this observation to hACE2 Tg mice that were resistant to the
lethal SARS-CoV infection. Interestingly, while the kinetics and magnitude of the cytokine …

… These animals express the hACE2 in various tissues … this virus spreads to K18- and
CAG-hACE2 transgenic mice. … virus, AC70 mice were found to be more susceptible to SARS-…