[HTML][HTML] Current status of therapeutic monoclonal antibodies against SARS-CoV-2

S Kumar, A Chandele, A Sharma - PLoS pathogens, 2021 - journals.plos.org
… The spike (S) protein of SARS-CoV-2 is the primary target of neutralizing antibodies (NAbs)
(Fig 1A). Therefore, NAbs against SARS-CoV-2 that have either been deployed for therapy

[HTML][HTML] Monoclonal antibodies for COVID-19 therapy and SARS-CoV-2 detection

YC Hwang, RM Lu, SC Su, PY Chiang, SH Ko… - Journal of Biomedical …, 2022 - Springer
… of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Ab drugs for use
as COVID-19 therapeutic agents. The detailed structure of the SARS-CoV-2 spike protein is …

Monoclonal antibody therapies against SARS-CoV-2

D Focosi, S McConnell, A Casadevall… - The Lancet Infectious …, 2022 - thelancet.com
… Many randomised clinical trials of mAb therapy and prophylaxis have been launched, initially
… against SARS-CoV-2 (panel 1) to identify the strengths and weaknesses of this therapeutic

Neutralisation sensitivity of SARS-CoV-2 omicron subvariants to therapeutic monoclonal antibodies

D Yamasoba, Y Kosugi, I Kimura, S Fujita… - The Lancet Infectious …, 2022 - thelancet.com
… of newly emerging SARS-CoV-2 variants, we suggest the importance of rapid evaluation
of the efficiency of therapeutic monoclonal antibodies against novel SARS-CoV-2 variants. …

[HTML][HTML] Mini-review: the market growth of diagnostic and therapeutic monoclonal antibodiesSARS CoV-2 as an example

Y El Abd, A Tabll, R Smolic, M Smolic - Human antibodies, 2022 - content.iospress.com
… of diagnostic and therapeutic monoclonal antibodies is the … grams of therapeutic monoclonal
antibodies annually but … production of diagnostic or therapeutic antibodies. Invivo and invitro …

Susceptibility of SARS-CoV-2 Omicron variants to therapeutic monoclonal antibodies: systematic review and meta-analysis

K Tao, PL Tzou, SL Kosakovsky Pond… - Microbiology …, 2022 - Am Soc Microbiol
… domain, the target of all authorized monoclonal antibodies (MAbs). … Monoclonal antibodies
(MAbs) targeting the SARS-CoV-2 … However, SARS-CoV-2 Omicron variants contain many …

[HTML][HTML] An infectious SARS-CoV-2 B. 1.1. 529 Omicron virus escapes neutralization by therapeutic monoclonal antibodies

LA VanBlargan, JM Errico, PJ Halfmann, SJ Zost… - Nature medicine, 2022 - nature.com
… syndrome coronavirus 2 (SARS-CoV-2) is concerning for antibody countermeasure efficacy
… In this study, we tested a panel of anti-receptor-binding domain monoclonal antibodies (…

Monoclonal antibody therapies in the management of SARS-CoV-2 infection

E Miguez-Rey, D Choi, S Kim, S Yoon… - … Investigational Drugs, 2022 - Taylor & Francis
… for SARS-CoV-2 infection, with a focus on the therapeutic application of neutralizing antibodies
… Current status of therapeutic monoclonal antibodies against SARS-CoV-2. PLoS Pathog. …

Double lock of a potent human therapeutic monoclonal antibody against SARS-CoV-2

L Zhu, YQ Deng, RR Zhang, Z Cui… - National Science …, 2021 - academic.oup.com
… human monoclonal antibody, HB27, that blocks SARS-CoV-2 … SARS-CoV-2 membrane
fusion. Consequently, a single dose of HB27 conferred effective protection against SARS-CoV-2 …

Analysis of SARS-CoV-2 mutations associated with resistance to therapeutic monoclonal antibodies that emerge after treatment.

D Focosi, S McConnell, DJ Sullivan… - Drug Resistance Updates, 2023 - Elsevier
… authorized anti-Spike monoclonal antibodies (mAbs). … The heterogenous therapeutic
management of those cases … of mAb therapies and a subsequent increase in SARS-CoV-2 …