[HTML][HTML] SARS-CoV-2: structure, biology, and structure-based therapeutics development

MY Wang, R Zhao, LJ Gao, XF Gao… - Frontiers in cellular …, 2020 - frontiersin.org
SARS-CoV-2. And particularly, we introduced the protein structures of SARS-CoV-2 and
structure-based therapeutics development … limitations and perspectives of SARS-CoV-2 research…

[HTML][HTML] Structural biology of SARS-CoV-2 and implications for therapeutic development

H Yang, Z Rao - Nature Reviews Microbiology, 2021 - nature.com
SARS-CoV-2 proteins can … of SARS-CoV-2 from the whole viral particle to the individual
viral proteins and discuss their functions as well as their potential as targets for therapeutic

[HTML][HTML] The spike protein of SARS-CoV—a target for vaccine and therapeutic development

L Du, Y He, Y Zhou, S Liu, BJ Zheng… - Nature Reviews …, 2009 - nature.com
… The SARS-CoV spike (S) protein is composed of two subunits; the S1 subunit … SARS-CoV.
In this Review, we highlight recent advances in the development of vaccines and therapeutics

[HTML][HTML] SARS-CoV-2/COVID-19 and advances in developing potential therapeutics and vaccines to counter this emerging pandemic

AA Rabaan, SH Al-Ahmed, R Sah, R Tiwari… - Annals of Clinical …, 2020 - Springer
… -2 virus belongs to the genus Betacoronavirus, like MERS-CoV and SARS-CoV, all of which
… basis of the SARS-CoV-2 infection and evolution, develop effective therapeutics, antiviral …

Prospect of SARS-CoV-2 spike protein: Potential role in vaccine and therapeutic development

SK Samrat, AM Tharappel, Z Li, H Li - Virus research, 2020 - Elsevier
… The role of the S protein in binding with host receptors makes it a perfect target for vaccine
and antiviral therapeutic development. Previous studies on SARS-CoV and MESR-CoV have …

[HTML][HTML] SARS-CoV-2 E protein: Pathogenesis and potential therapeutic development

S Zhou, P Lv, M Li, Z Chen, H Xin, S Reilly… - Biomedicine & …, 2023 - Elsevier
… of the SARS-CoV-2 E protein, and discuss its role in the viral life cycle and pathogenesis
process as well as the development of … structural motif for anti-SARS CoV-2 agent development. …

Drug development and medicinal chemistry efforts toward SARScoronavirus and Covid‐19 therapeutics

AK Ghosh, M Brindisi, D Shahabi… - …, 2020 - Wiley Online Library
… towards novel therapeutic options for both SARS-CoV and MERS-CoV could be of great
help to identify potential treatments for SARS-CoV-2. Among them, the development of broad-…

[HTML][HTML] Drug discovery strategies for SARS-CoV-2

ZA Shyr, K Gorshkov, CZ Chen, W Zheng - … and Experimental Therapeutics, 2020 - ASPET
… a practical therapeutic strategy for … developing vaccines and therapeutics against SARS-CoV-2.
This review highlights the anti–SARS-CoV-2 drug targets and therapeutic development

[HTML][HTML] Potential therapeutic targets and vaccine development for SARS-CoV-2/COVID-19 pandemic management: a review on the recent update

U Anand, S Jakhmola, O Indari, HC Jha… - Frontiers in …, 2021 - frontiersin.org
… and environment and anti-CoV therapeutic strategies; including vaccines and … of SARS-CoV-2
infection with the hope that this integrative analysis could help develop novel therapeutic

SARSCOV‐2 (COVID‐19): Cellular and biochemical properties and pharmacological insights into new therapeutic developments

H Parlakpinar, M Gunata - Cell Biochemistry and Function, 2021 - Wiley Online Library
… Many organizations use the published genomes of the virus to develop possible vaccines
against SARS-CoV-2. As of August 2020, there are 231 vaccine candidates in the development