Sars-escape network for escape prediction of SARS-COV-2
… To capture the semantics and grammaticality of the SARS-CoV-2 sequences, we designed
an escape learning network based on a bidirectional LSTM architecture [20] similar to the …
an escape learning network based on a bidirectional LSTM architecture [20] similar to the …
Risk of evolutionary escape from neutralizing antibodies targeting SARS-CoV-2 spike protein
D Van Egeren, A Novokhodko, M Stoddard, U Tran… - medRxiv, 2020 - medrxiv.org
… We estimated the total number of individuals infected with SARS-CoV-2 using the number
of diagnosed cases. As of 11/8/20, the number of active diagnosed cases worldwide is 14 …
of diagnosed cases. As of 11/8/20, the number of active diagnosed cases worldwide is 14 …
[HTML][HTML] A structural dynamic explanation for observed escape of SARS-CoV-2 BA. 2 variant mutation S371L/F
… and experimental escape measurements for … /F escape according to a perturbation of spike
trimer conformational dynamics that has not yet been described for any SARS-CoV-2 escape …
trimer conformational dynamics that has not yet been described for any SARS-CoV-2 escape …
Vaccine escape in a heterogeneous population: insights for SARS-CoV-2 from a simple model
… Rather than aiming to develop a detailed model of SARS-CoV-2 transmission dynamics,
we present a two-population model with differing vulnerability and contact rates to elucidate …
we present a two-population model with differing vulnerability and contact rates to elucidate …
[HTML][HTML] Evolution of SARS-CoV-2 variants: implications on immune escape, vaccination, therapeutic and diagnostic strategies
NZ Zabidi, HL Liew, IA Farouk, A Puniyamurti, AJW Yip… - Viruses, 2023 - mdpi.com
… of human coronaviruses, particularly SARS-CoV-2 and its … against SARS-CoV-2 and their
efficacy, including immune evasion by new variants and sub-variants. The impact of SARS-CoV…
efficacy, including immune evasion by new variants and sub-variants. The impact of SARS-CoV…
[HTML][HTML] Risk of rapid evolutionary escape from biomedical interventions targeting SARS-CoV-2 spike protein
D Van Egeren, A Novokhodko, M Stoddard, U Tran… - PloS one, 2021 - journals.plos.org
… We estimated the total number of individuals infected with SARS-CoV-2 using the number
of diagnosed cases. As of 11/8/20, the number of active diagnosed cases worldwide is 14 …
of diagnosed cases. As of 11/8/20, the number of active diagnosed cases worldwide is 14 …
[HTML][HTML] Development of potency, breadth and resilience to viral escape mutations in SARS-CoV-2 neutralizing antibodies
… in SARS-CoV-2 convalescence, we compared clonally-related antibodies, from six lineages
(Table S1), isolated at a mean of 1.3 or 6.2 months (m) after PCR diagnosis of SARS-CoV-2 …
(Table S1), isolated at a mean of 1.3 or 6.2 months (m) after PCR diagnosis of SARS-CoV-2 …
ESC: a comprehensive resource for SARS-CoV-2 immune escape variants
M Rophina, K Pandhare, A Shamnath… - Nucleic acids …, 2022 - academic.oup.com
… immune escape associated with genetic variants in SARS-CoV-… to retrieve information on
immune escape variants as well as … resource for immune escape variants for SARS-CoV-2. The …
immune escape variants as well as … resource for immune escape variants for SARS-CoV-2. The …
Evolution of a globally unique SARS-CoV-2 Spike E484T monoclonal antibody escape mutation in a persistently infected, immunocompromised individual
… Here, we report a 16 month-long SARS-CoV-2 infection in an … not been reported in public
SARS-CoV-2 sequence databases … proactive treatment for prolonged SARS-CoV-2 infections …
SARS-CoV-2 sequence databases … proactive treatment for prolonged SARS-CoV-2 infections …
[HTML][HTML] SARS-CoV-2 B. 1.617. 2 Delta variant replication and immune evasion
… that increased replication fitness and reduced sensitivity of SARS-CoV-2 B.1.617.2 to …
selection of escape variants where there is immune compromise and chronic SARS-CoV-2 …
selection of escape variants where there is immune compromise and chronic SARS-CoV-2 …