… found in the SARS-CoV-2 … the total number of SARS-CoV-2 sequences submitted each
month (denoted on the X-axis), and the blue represents the number of sequences among total …

… After analyzing SARS-CoV-2 spike … SARSCoV from the 2002 Hong Kong coronavirus
outbreak and pre-emergent bat-derived WIV1-CoV both share ~76% spike homology to SARS-CoV…

… raised issues about potential immune escape [2]. SARS-CoV-2 is an enveloped virus with
a positive-sense single-stranded RNA genome. It belongs to the β-coronavirus genus of the …

… ) and newly generated neutralizing mAbs against SARS-CoV-2 RBD to select for escape
variants and define the mutational landscape of resistance. To facilitate selection, we used a …

… is the dominating mechanism of SARS-CoV-2 evolution, … compared to that of the original
SARS-CoV-2 but can disrupt … mutations in more than 2.2 million SARS-CoV-2 genomes, we …

… the SARS-CoV-2 receptor-binding domain on both receptor affinity, which mediates viral
infectivity, and escape … These methods identify key mutations in current and former SARS-CoV-2 …

… the escape score of L455F/F456L and total escape scores on 455/456. Antibodies are split
into two groups according to their total escape scores on 455/456 as described in Fig 3B. …

… in distinct and rapidly spreading SARS-CoV-2 lineages suggests … shown to develop upon
natural SARS-CoV-2 infection [41] or … of SARS-CoV-2 variants with the potential to escape host …

… SARS-CoV-2 variant, the B.1.617.2 lineage with the S:E484Q mutation, and its rapid spread
and immune escape in … promotes biological selection with immune escape variants. Hence, …

… hotspots of SARS-CoV-2 RBD that can enable virus escape from … of the possible
immune-escaping hotspots on interactions with … agents against potential variants of SARS-CoV-2. …