… the causative agent as a novel SARS-related coronavirus (SARS-CoV-2) that uses human
… developed a SARS-CoV-2 hACE2 transgenic mouse (HFH4-hACE2 in C3B6 mice) infection …

… for severe acute respiratory syndrome coronavirus (SARS-CoV) 2 . Here we infected transgenic
mice that express human ACE2 (hereafter, hACE2 mice) with SARS-CoV-2 and studied …

… expression of hACE2 in mice. A mouse-adapted strain of SARS-CoV-2 containing 2 amino
… , which results in viral replication in the lungs of mice, and signs of pulmonary damage, but …

… transgenic mouse model for SARS coronavirus. We describe the method by which the hACE2
gene was introduced into the mouse … of hACE2 transgenic mice to SARS-CoV infection, …

… mouse ACE2 (mACE2) with the human ACE2. Further characterization demonstrated that
these humanized mice are highly susceptible to SARS-CoV-2 … that transgenic mice expressing …

… ) transgenic mouse model, which is susceptible to SARS-CoV-2 (30). In our pilot study, hACE2
transgenic mice were intranasally inoculated with SARS-CoV… ) virus per mouse] and were …

… Here, we evaluate transgenic mice expressing the human angiotensin I-converting enzyme
… of SARS-CoV-2 infection. Intranasal inoculation of SARS-CoV-2 in K18-hACE2 mice results …

… course of SARS-CoV-2 infection in K18-hACE2 transgenic mice. … mice, which observed
successful infection with SARS-CoV-2 and a milder disease severity compared with SARS-CoV-1…

… of SARS-CoV-2 infection. In this review, we summarize recent results from the studies involving
two such mouse … indirect impact of SARS-CoV-2 infection on the central nervous system. …

… transgenic mouse model 21 supports efficient SARS-CoV-2 replication and pathogenesis
in vivo. Thus, this transgenic mouse … that uses wild-type SARS-CoV-2 and is appropriate for …