… In this context, the hACE2 transgenic mouse under the … used mouse model to study the
pathogenetic effects of SARS-CoV-… Many of the SARS-CoV-2 antigen positive neurons of mice in …

… -VAC induced complete protection of the mice from a lethal SARS-CoV-2 challenge. Similar
viral … Cg-Tg(K18-hACE2)2Prlmn/J transgenic mice) of 6 weeks old were purchased from the …

… in response to the 2003 SARS outbreak, AC70 hACE2 transgenic mice were previously
extensively characterized in our laboratory for both SARS-CoV-1 and SARSCoV-2 (Drelich et al., …

… on mice regarding the susceptibility to SARS-CoV-2 except one on the transgenic mice with
… of rodent models such as BALB/c mice, C57BL/6 mice and golden Syrian hamsters to the …

… only found in a few cases of deceased COVID-19 patients (most of which were the elderly
with ages ranging from 51 to 94 years) and SARS-CoV-2-infected hACE2 transgenic mice. …

… /6, and BALB/c mice as compared with previous SARS-CoV-2 … Although K18-hACE2 transgenic
mice sustained infection in … in mice and hamsters, two key rodent models of SARS-CoV-2 …

… One of the studies examined the infectivity and pathological changes in SARS-CoV-2
infected transgenic hACE2 mice, which was developed using lung ciliated epithelial cell-specific …

… The resistance of WT mice to ancestral SARS-CoV-2 infection made transgenic hACE2 mice
one of … The K18-hACE2 mouse strain, a model used for SARS-CoV studies, is susceptible to …

… of mice. In this study, we used an alternative strategy to generate a SARS-CoV-2-sensitive
mouse … Similar to the results reported in SARS-CoV-2-infected transgenic mice, 3 VEEV-VRP-…

… Our results show that neither the E protein nor several SARS-CoV accessory proteins (6a,
7a, 7b, 8a, 8b, and 9b) are required for virus replication in vitro or in hACE2 Tg …