SARS-CoV-2 incidence and vaccine escape

RN Thompson, EM Hill, JR Gog - The Lancet Infectious Diseases, 2021 - thelancet.com
… In summary, high SARS-CoV-2 incidence rates act to increase the vaccine escape risk. …
and the potential for selection for vaccine escape variants in infected vaccinated hosts.A related …

A detailed overview of immune escape, antibody escape, partial vaccine escape of SARS-CoV-2 and their emerging variants with escape mutations

C Chakraborty, AR Sharma, M Bhattacharya… - Frontiers in …, 2022 - frontiersin.org
… variants’ partial vaccine (BioNTech/Pfizer … vaccine) escape ability. This review will help gain
in-depth knowledge related to immune escape, antibody escape, and partial vaccine escape

Evidence of escape of SARS-CoV-2 variant B. 1.351 from natural and vaccine-induced sera

D Zhou, W Dejnirattisai, P Supasa, C Liu, AJ Mentzer… - Cell, 2021 - cell.com
… race to produce vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
began when the first sequence was published, and this forms the basis for vaccines

[HTML][HTML] Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity

WF Garcia-Beltran, EC Lam, KS Denis, AD Nitido… - Cell, 2021 - cell.com
… globally circulating strains of SARS-CoV-2. Five … SARS-CoV and bat-derived WIV1-CoV,
suggesting that a relatively small number of mutations can mediate potent escape from vaccine

[HTML][HTML] SARS-CoV-2 variants, spike mutations and immune escape

WT Harvey, AM Carabelli, B Jackson… - Nature Reviews …, 2021 - nature.com
… that change the antigenic phenotype of SARS-CoV-2 are circulating and … SARS-CoV-2
(refs 12,13 ), and is the SARS-CoV-2 component of both mRNA and adenovirus-based vaccines

[HTML][HTML] SARS-CoV-2 variant biology: immune escape, transmission and fitness

AM Carabelli, TP Peacock, LG Thorne… - Nature Reviews …, 2023 - nature.com
… , first-generation SARS-CoV-2 vaccines conferred remarkable … vaccinated and previously
infected, bringing about the challenge of vaccine-sequence selection and universal vaccines

Vaccine escape in a heterogeneous population: insights for SARS-CoV-2 from a simple model

JR Gog, EM Hill, L Danon… - Royal Society Open …, 2021 - royalsocietypublishing.org
… among the population, infection and disease prevalence and vaccine escape. In … vaccine
escape risk might modulate optimal vaccine priority order. In particular, if infection in vaccinated

Emerging vaccine-breakthrough SARS-CoV-2 variants

R Wang, J Chen, Y Hozumi, C Yin… - ACS infectious …, 2022 - ACS Publications
… To understand the molecular mechanisms of vaccine-escape mutations, we analyze single
nucleotide polymorphisms (SNPs) of 1 489 884 complete SARS-CoV-2 genome sequences, …

Increased immune escape of the new SARS-CoV-2 variant of concern Omicron

J Hu, P Peng, X Cao, K Wu, J Chen, K Wang… - Cellular & Molecular …, 2022 - nature.com
… subunit vaccine sera against Omicron displays a lower fold-change (9.4 folds) than convalescent
sera (21.1 folds). We hypothesize that antibody affinity maturation induced by vaccines

Considerable escape of SARS-CoV-2 Omicron to antibody neutralization

D Planas, N Saunders, P Maes, F Guivel-Benhassine… - Nature, 2022 - nature.com
vaccine, as well as vaccination of previously infected individuals, strongly increased overall
levels of anti-SARS-CoV… the efficacy of the humoral anti-SARS-CoV-2 response over time 35,…