Atherosclerosis as pathogenetic substrate for Sars-Cov2 cytokine storm

M Vinciguerra, S Romiti, K Fattouch, A De Bellis… - Journal of Clinical …, 2020 - mdpi.com
… In patients who need ICU treatment and those with severe/critical manifestation of Sars-CoV-2, …
disproportionate activation of cytokine hosts in a cascade labeled a “cytokine storm” [7,9]. …

Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment

M Soy, G Keser, P Atagündüz, F Tabak… - Clinical …, 2020 - Springer
… Based on these observations, TCZ treatment was also tried in patients with severe SARS-CoV-2
infection complicated with cytokine storm and ARDS. Retrospective studies from China …

Effectiveness of corticoid pulses in patients with cytokine storm syndrome induced by SARS-CoV-2 infection

JLC Rubio, JDL Del Castillo… - … Clínica (English Edition), 2020 - Elsevier
SARS-CoV-2 disease (COVID-19).1, 2 The basis of its treatment is essentially tocilizumab,
an anti-IL-6 … other diseases in which there is a cytokine storm similar to the one that occurs in …

[HTML][HTML] Cytokine storm intervention in the early stages of COVID-19 pneumonia

X Sun, T Wang, D Cai, Z Hu, H Liao, L Zhi, H Wei… - Cytokine & growth factor …, 2020 - Elsevier
cytokine production in patients who are critically ill with SARS-CoV2-induced pneumonia. In
a retrospective study of 41 patients with COVID-19, most patients with SARS-… some patients

Comparison of the characteristics of cytokine storm and immune response induced by SARS-CoV, MERS-CoV, and SARS-CoV-2 infections

T Liu, M Feng, Z Wen, Y He, W Lin… - Journal of Inflammation …, 2021 - Taylor & Francis
… the characters of cytokine storms and immune … (SARS-CoV), Middle East respiratory
syndrome-coronavirus (MERS-CoV), and severe acute respiratory syndrome coronavirus 2 (SARS-…

[PDF][PDF] Coronavirus-19 (SARS-CoV-2) induces acute severe lung inflammation via IL-1 causing cytokine storm in COVID-19: a promising inhibitory strategy

P Conti, A Caraffa, CE Gallenga, R Ross… - J Biol Regul Homeost …, 2020 - researchgate.net
SARS-CoV-2 stimulates the secretion of IL-6 and TNF, a pro-inflammatory complex that can
lead to cytokine storm … In SARS-CoV-2 septic shock, severe metabolic cellular abnormalities …

Cytokine storm in COVID-19:“when you come out of the storm, you won't be the same person who walked in”

V Castelli, A Cimini, C Ferri - Frontiers in immunology, 2020 - frontiersin.org
… In contrast to SARS patients, however, individuals affected by COVID-19 also showed …
This analysis showed distinct host inflammatory cytokine profiles to SARS-CoV-2 infection and …

Therapeutic role of tocilizumab in SARS-CoV-2-induced cytokine storm: rationale and current evidence

C Pelaia, C Calabrese, E Garofalo, A Bruni… - International Journal of …, 2021 - mdpi.com
… , is often used to treat patients with severe COVID-19 symptoms … utilization in the SARS-CoV-2-triggered
cytokine storm, as well as … in patients with life-threatening SARS-CoV-2 infection. …

Influenza infection, SARS, MERS and COVID-19: cytokine storm–the common denominator and the lessons to be learned

VA Ryabkova, LP Churilov, Y Shoenfeld - Clinical Immunology, 2021 - Elsevier
… of patients with the cytokine storm [57]. The adaptive arm of the immune system is generally
considered to play a key role in the clearance of viruses and establishment of immunological …

ORF8 contributes to cytokine storm during SARS-CoV-2 infection by activating IL-17 pathway

X Lin, B Fu, S Yin, Z Li, H Liu, H Zhang, N Xing, Y Wang… - Iscience, 2021 - cell.com
SARS-CoV-2 coding protein open reading frame 8 (ORF8) acted as a contributing factor to
cytokine storm … to understand the pathogenesis of cytokine storm caused by SARS-CoV-2 and …