… -containing proteins include cargo receptors, members of the basal autophagy … by selective
autophagy. Here, we comment on these new insights and focus on the interactions of LIR-…

… motif (AIM) is also often used. In this review, we focus on the soluble mammalian SARs and
LIR–… further, we will first consider the ATG8 family proteins and the LIR motif interactions. …

… and Atg8-interacting motifs (AIMs) in … selective autophagy with a focus on the unifying
principles employed in substrate recognition, interaction with the forming autophagosome via LIR-…

… The first two aspartic acid residues in the LIR motif form electrostatic … LIR motif in p62, similar
motifs have been identified in numerous other ATG8 interactors, and a consensus LIR motif …

… selective autophagic process. In this review, we summarize the most up-to-date findings about
the structure-function of autophagy receptors that regulates selective autophagy… LIR motif, …

… Here, we review the mechanistic basis of selective autophagy in … The emerging picture of
selective autophagy affecting the … We mapped two LIR motifs in NBR1 of which LIR1, centered …

… In order to examine whether selective autophagy can be modulated by disrupting LIR
interactions, we have generated affinity reagents that target the LIR motif of the SARs optineurin, …

… for selective autophagy, members of the core autophagy … (fusion to lysosomes) of
autophagosomes. Protein binding to … sequence motifs known as LC3-interacting regions (LIRs). …

… role of AIM/LIR motifs in selective autophagy. In particular, we found that the S. cerevisiae
cargo receptor Atg19 directly binds to the Atg5 subunit of the Atg12–Atg5-Atg16 complex ( Fig. …

… selectivity is achieved in this process. Here, we summarize the mechanistic and structural
basis of receptor-mediated selective autophagy. … , LIR motifs are not restricted to autophagy …