Real-time selective sequencing using nanopore technology

M Loose, S Malla, M Stout - Nature methods, 2016 - nature.com
… The anticipated speed increases in nanopore sequencing ('fast mode' is currently 300 b/s …
that selective sequencing will enable new approaches such as exon sequencing without target …

Selective nanopore sequencing of human BRCA1 by Cas9-assisted targeting of chromosome segments (CATCH)

T Gabrieli, H Sharim, D Fridman, N Arbib… - Nucleic acids …, 2018 - academic.oup.com
… for targeted nanopore sequencing and showed an enrichment factor of 21.7 for sequencing
of a … Here, we harness CATCH for nanopore and NGS sequencing of human BRCA1, a large …

DeepSelectNet: deep neural network based selective sequencing for oxford nanopore sequencing

A Senanayake, H Gamaarachchi, D Herath, R Ragel - BMC bioinformatics, 2023 - Springer
Nanopore sequencing allows selective sequencing, the ability to programmatically reject
unwanted reads in a sample. Selective sequencing … Existing methods for selective sequencing

Accelerated dynamic time warping on GPU for selective nanopore sequencing

H Sadasivan, D Stiffler, A Tirumala, J Israeli… - bioRxiv, 2023 - biorxiv.org
… we present DTWax, a GPU-accelerated sDTW software for nanopore Read Until to save
time and cost of nanopore sequencing and compute. We adapt SquiggleFilter ASIC 4 ’s …

Nanopore sequencing: from imagination to reality

H Bayley - Clinical chemistry, 2015 - academic.oup.com
… signals from related analytes (eg, various divalent metal ions or structurally related organic
molecules) differ, the engineered binding site does not have to be absolutely selective for an …

A large size-selective DNA nanopore with sensing applications

RP Thomsen, MG Malle, AH Okholm, S Krishnan… - Nature …, 2019 - nature.com
… system that allowed size-selective gating of translocation through the pore. Finally, we turned
the DNA nanopore into a biosensor by demonstrating sequence-specific unplugging and …

Genome enrichment of rare and unknown species from complicated microbiomes by nanopore selective sequencing

Y Sun, Z Cheng, X Li, Q Yang, B Zhao, Z Wu… - Genome …, 2023 - genome.cshlp.org
… low-abundance species, selective sequencing provides a … samples by selective sequencing
remains challenging … protocol for configuring selective nanopore sequencing and necessary …

Nanopore-based technologies beyond DNA sequencing

YL Ying, ZL Hu, S Zhang, Y Qing, A Fragasso… - Nature …, 2022 - nature.com
… of nanopores in molecular sensing and sequencing, chemical … nanopores for single-protein
analysis and sequencing, single-… Selective transport across individual biomimetic nanopores

Readfish enables targeted nanopore sequencing of gigabase-sized genomes

A Payne, N Holmes, T Clarke, R Munro… - Nature …, 2021 - nature.com
Nanopore sequencers can be used to selectively sequence certain DNA molecules in a pool
by reversing the voltage across individual nanopores … in <15 h sequencing. These methods …

ReadCurrent: a VDCNN-based tool for fast and accurate nanopore selective sequencing

K Fan, M Li, J Zhang, Z Xie, D Jiang, X Bo… - Briefings in …, 2024 - academic.oup.com
nanopore selective sequencing. Here, we present a DL-based tool named ReadCurrent for
nanopore selective sequencing, … across 10 nanopore sequencing datasets spanning human, …