SARS-CoV-2 host tropism: An in silico analysis of the main cellular factors

HR Rangel, JT Ortega, S Maksoud, FH Pujol… - Virus Research, 2020 - Elsevier
… stages driving host selectivity for SARS-CoV-2. Similar to SARS-CoV, SARS-CoV-2 infection
… Previously, we predicted that the changes in the SARS-CoV-2 viral spike protein improved …

SARS-CoV-2: receptor and co-receptor tropism probability

N Eslami, PS Aghbash, A Shamekh… - Current …, 2022 - Springer
… This review investigates multiple current types of receptor and co-receptor tropisms, with …
and entry of SARS-CoV-2 into the cells, extending the severity of the coronavirus disease 2019 (…

Ten emerging SARS-CoV-2 spike variants exhibit variable infectivity, animal tropism, and antibody neutralization

L Zhang, Z Cui, Q Li, B Wang, Y Yu, J Wu, J Nie… - Communications …, 2021 - nature.com
… and host tropism of 10 SARS-CoV-2 variants. The infectivities of most tested SARS-CoV-2 …
mutations change host tropism, implying possible transmission of SARS-CoV-2 variants in …

Multiorgan and vascular tropism of SARS-CoV-2

C Hartard, A Chaqroun, N Settembre, G Gauchotte… - Viruses, 2022 - mdpi.com
… of SARS-CoV-2, other tissues and organs are permissive to the infection. In this report, we
investigated this wide-spectrum tropism by studying the SARS-CoVSARS-CoV-2 genome was …

Host cell entry mediators implicated in the cellular tropism of SARSCoV‑2, the pathophysiology of COVID‑19 and the identification of microRNAs that can modulate …

P Katopodis, HS Randeva… - International …, 2022 - spandidos-publications.com
… severe acute respiratory syndrome coronavirus 2 (SARSCoV‑2) … overview of the ‘canonical’
SARSCoV‑2 mediators, namely … between the cellular tropism of the SARSCoV‑2 cell entry …

Cardiovascular tropism and sequelae of SARS-CoV-2 infection

O Dmytrenko, KJ Lavine - Viruses, 2022 - mdpi.com
… sites are susceptible to SARS-CoV-2 infection [73,74,75]. Cellular tropism outside of the
lung seems to be dictated by ACE2 expression and the ability of the virus to gain access to …

SARS-CoV-2 and SARS-CoV differ in their cell tropism and drug sensitivity profiles

D Bojkova, JE McGreig, KM McLaughlin, SG Masterson… - BioRxiv, 2020 - biorxiv.org
… between SARS-CoV-2 and the closely related SARS-CoV, are … tropism of SARS-CoV-2
and SARS-CoV. Moreover, cellular ACE2 (SARS-CoV-2 receptor) and TMPRSS2 (enables virus

Analysis of the tropism of SARS-CoV-2 based on the host interactome of the spike protein

C Bamberger, S Pankow… - Journal of Proteome …, 2023 - ACS Publications
… We speculate that an expanded tropism of SARS-CoV-2 might shed light on the prolonged
progression of COVID-19 in select patients. A pCtSEA analysis may indicate whether a virus-…

Nervous system‐related tropism of SARSCoV‐2 and autoimmunity in COVID‐19 infection

R Weissert - European Journal of Immunology, 2024 - Wiley Online Library
… In this review, the current understanding of SARS- CoV-2 tropism for the nervous system,
the associated … The data indicates that there is viral tropism of SARS-CoV-2 for the nervous …

Determination of the factors responsible for the tropism of SARS-CoV-2-related bat coronaviruses to Rhinolophus bat ACE2

S Fujita, Y Kosugi, I Kimura, K Tokunaga, J Ito… - Journal of …, 2023 - Am Soc Microbiol
tropisms for Rhinolophus bat ACE2. Through structural analysis and cell culture experiments,
we demonstrate that this tropism is … -CoVs exhibit differential ACE2 tropism, which may be …